BioFarma
Biología de membranas y mecanismos de transducción de señales en farmacología aplicada.
Publicaciones (396) Publicaciones en las que ha participado algún/a investigador/a
2024
-
2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives
Molecules, Vol. 29, Núm. 11
-
Altered dynamics of calcium fluxes and mitochondrial metabolism in platelet activation-related disease and aging
Life Sciences, Vol. 351
-
Design, synthesis and validation of a new Crimped Head-Piece for DNA-Encoded libraries generation
Bioorganic and Medicinal Chemistry, Vol. 99
-
Discovery and in vitro Evaluation of Novel Serotonin 5-HT2A Receptor Ligands Identified Through Virtual Screening
ChemMedChem, Vol. 19, Núm. 14
-
Effect of Bulky N-Dibenzofuranylmethyl Substitution on the 5-HT2 Receptor Affinity and Efficacy of a Psychedelic Phenethylamine
ACS Chemical Neuroscience, Vol. 15, Núm. 3, pp. 608-616
-
Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents
Biomedicine and Pharmacotherapy, Vol. 173
-
G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits
Nature communications, Vol. 15, Núm. 1, pp. 4307
-
High-Throughput DNA-Encoded Libraries Affinity Selection Platform for Binder Identification with Solid Support Protein Immobilization
Assay and Drug Development Technologies, Vol. 22, Núm. 4, pp. 192-202
-
High-throughput nephelometry methodology for qualitative determination of aqueous solubility of chemical libraries
SLAS Discovery, Vol. 29, Núm. 3
-
In vitro models for neuropathic pain phenotypic screening in brain therapeutics
Pharmacological Research, Vol. 202
-
N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)
Journal of Medicinal Chemistry, Vol. 67, Núm. 13, pp. 11003-11023
-
Nanoemulsions and nanocapsules as carriers for the development of intranasal mRNA vaccines
Drug Delivery and Translational Research, Vol. 14, Núm. 8, pp. 2046-2061
-
Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics
Scientific Reports, Vol. 14, Núm. 1
2023
-
8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies
European Journal of Medicinal Chemistry, Vol. 248
-
A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery
Molecules, Vol. 28, Núm. 24
-
A continuous in silico learning strategy to identify safety liabilities in compounds used in the leather and textile industry
Archives of Toxicology, Vol. 97, Núm. 4, pp. 1091-1111
-
Design and biopharmaceutical preclinical characterisation of a new thermosensitive hydrogel for the removal of gastric polyps
International Journal of Pharmaceutics, Vol. 635, pp. 122706
-
Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia
Molecules, Vol. 28, Núm. 10
-
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase
Journal of Medicinal Chemistry, Vol. 66, Núm. 1, pp. 235-250
-
Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents – Design, synthesis, structural studies and pharmacological profiling
European Journal of Medicinal Chemistry, Vol. 252