Publikationen (391) Publikationen, an denen Forscher/innen teilgenommen haben

2024

  1. 2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives

    Molecules, Vol. 29, Núm. 11

  2. Altered dynamics of calcium fluxes and mitochondrial metabolism in platelet activation-related disease and aging

    Life Sciences, Vol. 351

  3. Design, synthesis and validation of a new Crimped Head-Piece for DNA-Encoded libraries generation

    Bioorganic and Medicinal Chemistry, Vol. 99

  4. Discovery and in vitro Evaluation of Novel Serotonin 5-HT2A Receptor Ligands Identified Through Virtual Screening

    ChemMedChem

  5. Effect of Bulky N-Dibenzofuranylmethyl Substitution on the 5-HT2 Receptor Affinity and Efficacy of a Psychedelic Phenethylamine

    ACS Chemical Neuroscience, Vol. 15, Núm. 3, pp. 608-616

  6. Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents

    Biomedicine and Pharmacotherapy, Vol. 173

  7. G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits

    Nature communications, Vol. 15, Núm. 1, pp. 4307

  8. High-Throughput DNA-Encoded Libraries Affinity Selection Platform for Binder Identification with Solid Support Protein Immobilization

    Assay and Drug Development Technologies, Vol. 22, Núm. 4, pp. 192-202

  9. High-throughput nephelometry methodology for qualitative determination of aqueous solubility of chemical libraries

    SLAS Discovery, Vol. 29, Núm. 3

  10. In vitro models for neuropathic pain phenotypic screening in brain therapeutics

    Pharmacological Research, Vol. 202

  11. N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)

    Journal of Medicinal Chemistry

  12. Nanoemulsions and nanocapsules as carriers for the development of intranasal mRNA vaccines

    Drug Delivery and Translational Research, Vol. 14, Núm. 8, pp. 2046-2061

  13. Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics

    Scientific Reports, Vol. 14, Núm. 1

2023

  1. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    European Journal of Medicinal Chemistry, Vol. 248

  2. A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery

    Molecules, Vol. 28, Núm. 24

  3. A continuous in silico learning strategy to identify safety liabilities in compounds used in the leather and textile industry

    Archives of Toxicology, Vol. 97, Núm. 4, pp. 1091-1111

  4. Design and biopharmaceutical preclinical characterisation of a new thermosensitive hydrogel for the removal of gastric polyps

    International Journal of Pharmaceutics, Vol. 635, pp. 122706

  5. Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia

    Molecules, Vol. 28, Núm. 10

  6. Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase

    Journal of Medicinal Chemistry, Vol. 66, Núm. 1, pp. 235-250

  7. Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents – Design, synthesis, structural studies and pharmacological profiling

    European Journal of Medicinal Chemistry, Vol. 252