BioFarma
Applied pharmacology to membrane biology and signal transduction mechanisms.
Publications (399) Publications in which a researcher has participated
2024
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2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives
Molecules, Vol. 29, Núm. 11
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Altered dynamics of calcium fluxes and mitochondrial metabolism in platelet activation-related disease and aging
Life Sciences, Vol. 351
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Design, synthesis and validation of a new Crimped Head-Piece for DNA-Encoded libraries generation
Bioorganic and Medicinal Chemistry, Vol. 99
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Design, synthesis, and biological evaluation of tetrahydropyrimidine analogue as GSK-3β/Aβ aggregation inhibitor and anti-Alzheimer's agent
Bioorganic Chemistry, Vol. 153
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Discovery and in vitro Evaluation of Novel Serotonin 5-HT2A Receptor Ligands Identified Through Virtual Screening
ChemMedChem, Vol. 19, Núm. 14
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Effect of Bulky N-Dibenzofuranylmethyl Substitution on the 5-HT2 Receptor Affinity and Efficacy of a Psychedelic Phenethylamine
ACS Chemical Neuroscience, Vol. 15, Núm. 3, pp. 608-616
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Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents
Biomedicine and Pharmacotherapy, Vol. 173
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Fármacos analgésicos opiáceos
Castells Hernández farmacología en enfermería (Elsevier), pp. 124-134
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G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits
Nature communications, Vol. 15, Núm. 1, pp. 4307
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High-Throughput DNA-Encoded Libraries Affinity Selection Platform for Binder Identification with Solid Support Protein Immobilization
Assay and Drug Development Technologies, Vol. 22, Núm. 4, pp. 192-202
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High-throughput nephelometry methodology for qualitative determination of aqueous solubility of chemical libraries
SLAS Discovery, Vol. 29, Núm. 3
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In vitro models for neuropathic pain phenotypic screening in brain therapeutics
Pharmacological Research, Vol. 202
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N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)
Journal of Medicinal Chemistry, Vol. 67, Núm. 13, pp. 11003-11023
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Nanoemulsions and nanocapsules as carriers for the development of intranasal mRNA vaccines
Drug Delivery and Translational Research, Vol. 14, Núm. 8, pp. 2046-2061
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Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties
Pharmaceutics, Vol. 16, Núm. 8
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Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics
Scientific Reports, Vol. 14, Núm. 1
2023
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8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies
European Journal of Medicinal Chemistry, Vol. 248
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A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery
Molecules, Vol. 28, Núm. 24
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A continuous in silico learning strategy to identify safety liabilities in compounds used in the leather and textile industry
Archives of Toxicology, Vol. 97, Núm. 4, pp. 1091-1111
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Design and biopharmaceutical preclinical characterisation of a new thermosensitive hydrogel for the removal of gastric polyps
International Journal of Pharmaceutics, Vol. 635, pp. 122706