Nanocarriers for enhancing the performance of immunomodulatory molecules

  1. Olivera Fernández, Ana
Supervised by:
  1. Dolores Torres López Director
  2. María José Alonso Fernández Director

Defence university: Universidade de Santiago de Compostela

Fecha de defensa: 13 October 2020

Committee:
  1. Felipe García Alcaide Chair
  2. Carlos Diéguez González Secretary
  3. Maria Marlow Committee member
Department:
  1. Department of Pharmacology, Pharmacy and Pharmaceutical Technology

Type: Thesis

Teseo: 637210 DIALNET lock_openMINERVA editor

Abstract

Nanotechnology offers the possibility of enhancing the performance of immunomodulatory molecules by facilitating their transport across biological barriers and targeting them to the immune system. Considering this promising potential, this thesis has focused on the development of polymeric nanocarriers loaded with an immunomodulatory molecule for the prevention of type 1 diabetes. Furthermore, pursuing the transdermal supplementation of this molecule, these nanocarriers were optimized to enhance its penetration across the skin.