Nanocarriers for enhancing the performance of immunomodulatory molecules

  1. Olivera Fernández, Ana
unter der Leitung von:
  1. Dolores Torres López Doktormutter
  2. María José Alonso Fernández Doktormutter

Universität der Verteidigung: Universidade de Santiago de Compostela

Fecha de defensa: 13 von Oktober von 2020

Gericht:
  1. Felipe García Alcaide Präsident/in
  2. Carlos Diéguez González Sekretär
  3. Maria Marlow Vocal
Fachbereiche:
  1. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica

Art: Dissertation

Teseo: 637210 DIALNET lock_openMINERVA editor

Zusammenfassung

Nanotechnology offers the possibility of enhancing the performance of immunomodulatory molecules by facilitating their transport across biological barriers and targeting them to the immune system. Considering this promising potential, this thesis has focused on the development of polymeric nanocarriers loaded with an immunomodulatory molecule for the prevention of type 1 diabetes. Furthermore, pursuing the transdermal supplementation of this molecule, these nanocarriers were optimized to enhance its penetration across the skin.