Departamento de Química Orgánica
Departamento
Imperial College London
Londres, Reino UnidoPublicacións en colaboración con investigadores/as de Imperial College London (15)
2023
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Dimeric Metal-Salphen Complexes Which Target Multimeric G-Quadruplex DNA
Bioconjugate Chemistry, Vol. 34, Núm. 5, pp. 911-921
2021
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A Suite of Activity-Based Probes to Dissect the KLK Activome in Drug-Resistant Prostate Cancer
Journal of the American Chemical Society, Vol. 143, Núm. 23, pp. 8911-8924
2020
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Antibody-PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4
ACS Chemical Biology, Vol. 15, Núm. 6, pp. 1306-1312
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Hanessian-Hullar reaction in the synthesis of highly substituted trans-3,4-dihydroxypyrrolidines: Rhamnulose iminosugar mimics inhibit α-glucosidase
Tetrahedron, Vol. 76, Núm. 1
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The Missing Link between (Un)druggable and Degradable KRAS
ACS Central Science, Vol. 6, Núm. 8, pp. 1281-1284
2017
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Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases
Journal of Cheminformatics, Vol. 9, Núm. 1
2016
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6-Deoxyhexoses from l-Rhamnose in the Search for Inducers of the Rhamnose Operon: Synergy of Chemistry and Biotechnology
Chemistry - A European Journal, Vol. 22, Núm. 35, pp. 12557-12565
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Synthetic Chemical Inducers and Genetic Decoupling Enable Orthogonal Control of the rhaBAD Promoter
ACS Synthetic Biology, Vol. 5, Núm. 10, pp. 1136-1145
2010
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Chiral aziridination of olefins using a chiral sulfanamide as the nitrogen source
Synlett, pp. 145-149
1999
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Total synthesis of the cholesterol biosynthesis inhibitor 1233A via a (π-allyl)tricarbonyliron lactone complex
Journal of the Chemical Society - Perkin Transactions 1, pp. 1917-1925
1988
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Formal synthesis of the antitumour antibiotic CC-1065
Journal of the Chemical Society, Perkin Transactions 1, pp. 2491-2499
1987
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Synthesis of the combined centre- and right-hand section of the antitumour agent CC-1065
Tetrahedron Letters, Vol. 28, Núm. 27, pp. 3163-3166
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Vinyl azides in heterocyclic synthesis. Part 8. Synthesis of the naturally occurring phosphodiesterase inhibitors PDE-I and PDE-II
Journal of the Chemical Society, Perkin Transactions 1, pp. 931-935
1986
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Synthesis of the left-hand unit of the antitumour agent CC-1065
Journal of the Chemical Society, Chemical Communications, pp. 1062-1063
1985
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Synthesis of the phosphodiesterase inhibitors PDE-I and PDE-II
Journal of the Chemical Society, Chemical Communications, pp. 1775-1776