ERNESTO
CANO RUBIO
Investigador en el periodo 1989-2018
Publicaciones en las que colabora con ERNESTO CANO RUBIO (37)
2019
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Novel compounds of hybrid structure pyridazinone-coumarin as potent inhibitors of platelet aggregation
Future medicinal chemistry, Vol. 11, Núm. 16, pp. 2051-2062
2017
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3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation
ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933
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Synthesis and vasorelaxant and antiplatelet activities of a new series of (4-Benzylphthalazin-1-ylamino)alcohol derivatives
Medicinal Chemistry Research, Vol. 26, Núm. 8, pp. 1682-1688
2015
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New platelet aggregation inhibitors based on pyridazinone moiety
European Journal of Medicinal Chemistry, Vol. 94, pp. 113-122
2012
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Discovery and preliminary SAR of 5-arylidene-2,2-dimethyl-1,3-dioxane-4,6- diones as platelet aggregation inhibitors
Combinatorial Chemistry and High Throughput Screening, Vol. 15, Núm. 7, pp. 551-554
2008
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2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: Design, synthesis, and SAR studies
Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 2, pp. 793-797
2007
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Design, synthesis, and structure-activity relationships of a novel series of 5-alkylidenepyridazin-3(2H)-ones with a non-cAMP-based antiplatelet activity
Journal of Medicinal Chemistry, Vol. 50, Núm. 26, pp. 6476-6484
2006
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(-)-Trans-ε-viniferin, a polyphenol present in wines, is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity
European Journal of Pharmacology, Vol. 542, Núm. 1-3, pp. 54-60
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Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin-resveratrol hybrids
Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 2, pp. 257-261
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Differential regulation of platelet aggregation and aminophospholipid exposure by calpain
British Journal of Haematology, Vol. 133, Núm. 4, pp. 419-426
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Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase activity
Biochemical and Biophysical Research Communications, Vol. 344, Núm. 2, pp. 688-695
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Parallel regulation by olanzapine of the patterns of expression of 5-HT2A and D3 receptors in rat central nervous system and blood cells
Neuropharmacology, Vol. 51, Núm. 4, pp. 923-932
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Pyridazines part 41: Synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl) pyridazin-3(2H)-ones
Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 4, pp. 1080-1083
2005
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β-Hexosaminidase isoenzyme profiles in serum, plasma, platelets and mononuclear, polymorphonuclear and unfractionated total leukocytes
Clinical Biochemistry, Vol. 38, Núm. 10, pp. 938-942
2004
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Antioxidant activity and inhibitory effects of hydralazine on inducible NOS/COX-2 gene and protein expression in rat peritoneal macrophages
International Immunopharmacology, Vol. 4, Núm. 2, pp. 163-177
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Efectos cardiovasculares y antitrombóticos de los isómeros CIS y Trans del Resveratrol: Estudio comparativo
Actualidad en farmacología y terapéutica, Vol. 2, Núm. 3, pp. 222-225
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In vitro effects of resveratrol on the viability and infectivity of the microsporidian Encephalitozoon cuniculi
Antimicrobial Agents and Chemotherapy, Vol. 48, Núm. 7, pp. 2497-2501
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Pyridazines. Part 36: Synthesis and antiplatelet activity of 5-substituted-6-phenyl-3(2H)-pyridazinones
Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 2, pp. 321-324
2002
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Pyridazines. Part 28: 5-Alkylidene-6-phenyl-3(2H)-pyridazinones, a new family of platelet aggregation inhibitors
Bioorganic and Medicinal Chemistry Letters, Vol. 12, Núm. 12, pp. 1575-1577
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Pyridazines. Part 31: Synthesis and antiplatelet activity of 4,5-disubstituted-6-phenyl-3(2H)-pyridazinones
Chemical and Pharmaceutical Bulletin, Vol. 50, Núm. 12, pp. 1574-1577