Publikationen, an denen er mitarbeitet ERNESTO CANO RUBIO (37)

2019

  1. Novel compounds of hybrid structure pyridazinone-coumarin as potent inhibitors of platelet aggregation

    Future medicinal chemistry, Vol. 11, Núm. 16, pp. 2051-2062

2017

  1. 3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation

    ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933

  2. Synthesis and vasorelaxant and antiplatelet activities of a new series of (4-Benzylphthalazin-1-ylamino)alcohol derivatives

    Medicinal Chemistry Research, Vol. 26, Núm. 8, pp. 1682-1688

2015

  1. New platelet aggregation inhibitors based on pyridazinone moiety

    European Journal of Medicinal Chemistry, Vol. 94, pp. 113-122

2012

  1. Discovery and preliminary SAR of 5-arylidene-2,2-dimethyl-1,3-dioxane-4,6- diones as platelet aggregation inhibitors

    Combinatorial Chemistry and High Throughput Screening, Vol. 15, Núm. 7, pp. 551-554

2008

  1. 2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: Design, synthesis, and SAR studies

    Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 2, pp. 793-797

2007

  1. Design, synthesis, and structure-activity relationships of a novel series of 5-alkylidenepyridazin-3(2H)-ones with a non-cAMP-based antiplatelet activity

    Journal of Medicinal Chemistry, Vol. 50, Núm. 26, pp. 6476-6484

2006

  1. (-)-Trans-ε-viniferin, a polyphenol present in wines, is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity

    European Journal of Pharmacology, Vol. 542, Núm. 1-3, pp. 54-60

  2. Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin-resveratrol hybrids

    Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 2, pp. 257-261

  3. Differential regulation of platelet aggregation and aminophospholipid exposure by calpain

    British Journal of Haematology, Vol. 133, Núm. 4, pp. 419-426

  4. Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase activity

    Biochemical and Biophysical Research Communications, Vol. 344, Núm. 2, pp. 688-695

  5. Parallel regulation by olanzapine of the patterns of expression of 5-HT2A and D3 receptors in rat central nervous system and blood cells

    Neuropharmacology, Vol. 51, Núm. 4, pp. 923-932

  6. Pyridazines part 41: Synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl) pyridazin-3(2H)-ones

    Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 4, pp. 1080-1083

2005

  1. β-Hexosaminidase isoenzyme profiles in serum, plasma, platelets and mononuclear, polymorphonuclear and unfractionated total leukocytes

    Clinical Biochemistry, Vol. 38, Núm. 10, pp. 938-942

2004

  1. Antioxidant activity and inhibitory effects of hydralazine on inducible NOS/COX-2 gene and protein expression in rat peritoneal macrophages

    International Immunopharmacology, Vol. 4, Núm. 2, pp. 163-177

  2. Efectos cardiovasculares y antitrombóticos de los isómeros CIS y Trans del Resveratrol: Estudio comparativo

    Actualidad en farmacología y terapéutica, Vol. 2, Núm. 3, pp. 222-225

  3. In vitro effects of resveratrol on the viability and infectivity of the microsporidian Encephalitozoon cuniculi

    Antimicrobial Agents and Chemotherapy, Vol. 48, Núm. 7, pp. 2497-2501

  4. Pyridazines. Part 36: Synthesis and antiplatelet activity of 5-substituted-6-phenyl-3(2H)-pyridazinones

    Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 2, pp. 321-324

2002

  1. Pyridazines. Part 28: 5-Alkylidene-6-phenyl-3(2H)-pyridazinones, a new family of platelet aggregation inhibitors

    Bioorganic and Medicinal Chemistry Letters, Vol. 12, Núm. 12, pp. 1575-1577

  2. Pyridazines. Part 31: Synthesis and antiplatelet activity of 4,5-disubstituted-6-phenyl-3(2H)-pyridazinones

    Chemical and Pharmaceutical Bulletin, Vol. 50, Núm. 12, pp. 1574-1577