Publicaciones (67) Publicaciones de RAMON SOTO OTERO

2024

  1. Copper Overload Increased Rat Striatal Levels of Both Dopamine and Its Main Metabolite Homovanillic Acid in Extracellular Fluid

    International Journal of Molecular Sciences, Vol. 25, Núm. 15

2023

  1. Assessment of Oxidative Stress Markers in Hypertensive Patients under the Use of Renin-Angiotensin-Aldosterone Blockers

    Antioxidants, Vol. 12, Núm. 4

  2. Implications of Inflammatory and Oxidative Stress Markers in the Attenuation of Nocturnal Blood Pressure Dipping

    Journal of Clinical Medicine, Vol. 12, Núm. 4

2022

  1. Assessment of oxidative stress markers in elderly patients with SARS-CoV-2 infection and potential prognostic implications in the medium and long term

    PloS one, Vol. 17, Núm. 10, pp. e0268871

  2. Correlation between Blunted Nocturnal Decrease in Diastolic Blood Pressure and Oxidative Stress: An Observational Study

    Antioxidants, Vol. 11, Núm. 12

2019

  1. Copper Increases Brain Oxidative Stress and Enhances the Ability of 6-Hydroxydopamine to Cause Dopaminergic Degeneration in a Rat Model of Parkinson’s Disease

    Molecular Neurobiology, Vol. 56, Núm. 4, pp. 2845-2854

2017

  1. Copper increases the ability of 6-hydroxydopamine to generate oxidative stress and the ability of ascorbate and glutathione to potentiate this effect: potential implications in Parkinson's disease

    Journal of Neurochemistry, Vol. 141, Núm. 5, pp. 738-749

  2. Effects of Aluminium on Rat Brain Mitochondria Bioenergetics: an In vitro and In vivo Study

    Molecular Neurobiology, Vol. 54, Núm. 1, pp. 563-570

2016

  1. 8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease

    ChemistrySelect, Vol. 1, Núm. 11, pp. 2742-2749

  2. Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents

    Journal of Medicinal Chemistry, Vol. 59, Núm. 14, pp. 6791-6806

  3. Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration

    Cell Death and Disease, Vol. 7, Núm. 10

  4. Searching for multi-targeting neurotherapeutics against Alzheimer's: Discovery of potent AChE-MAO B inhibitors through the decoration of the 2H-Chromen-2-one structural motif

    Molecules, Vol. 21, Núm. 3

2015

  1. In silico design of novel 2H-chromen-2-one derivatives as potent and selective MAO-B inhibitors

    European Journal of Medicinal Chemistry, Vol. 89, pp. 98-105

  2. Structure-Based Design and Optimization of Multitarget-Directed 2 H -Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases

    Journal of Medicinal Chemistry, Vol. 58, Núm. 14, pp. 5561-5578

2013

  1. A simple method for isolating rat brain mitochondria with high metabolic activity: Effects of EDTA and EGTA

    Journal of Neuroscience Methods, Vol. 213, Núm. 1, pp. 39-42

  2. Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors

    Journal of Medicinal Chemistry, Vol. 56, Núm. 6, pp. 2651-2664

  3. Fine molecular tuning at position 4 of 2H-chromen-2-one derivatives in the search of potent and selective monoamine oxidase B inhibitors

    European Journal of Medicinal Chemistry, Vol. 70, pp. 723-739

2012

  1. 2-Benzazepine nitrones protect dopaminergic neurons against 6-hydroxydopamine-induced oxidative toxicity

    Archiv der Pharmazie, Vol. 345, Núm. 8, pp. 598-609

  2. Differential toxicity of 6-hydroxydopamine in SH-SY5Y human neuroblastoma cells and rat brain mitochondria: Protective role of catalase and superoxide dismutase

    Neurochemical Research, Vol. 37, Núm. 10, pp. 2150-2160

2011

  1. Antioxidant properties of dimethyl sulfoxide and its viability as a solvent in the evaluation of neuroprotective antioxidants

    Journal of Pharmacological and Toxicological Methods, Vol. 63, Núm. 2, pp. 209-215