Departamento: Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica

Facultade: Facultade de Farmacia

Centro singular : Centro de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS)

Área: Farmacoloxía

Grupo de investigación: Bioloxía de membranas e mecanismos de transducción de sinais en farmacoloxía aplicada.

Correo el.: marian.castro@usc.es

Web persoal: https://www.usc.es/cimus/en/research/research-groups/mole...

Doutora pola Universidad Complutense de Madrid coa tese Receptores opioides mu y delta formas moleculares y posibles subtipos. Acoplamiento específico de agonista con proteínas transductoras gi2 y gx/z 1998. Dirixida por Dr/a. Javier Garzón Niño.

Marián (María de los Ángeles) Castro studied Pharmacy at the University of Santiago de Compostela. She obtained her Ph.D. at Instituto Cajal, CSIC, Madrid, in 1997, in the field of Neuropharmacology of Opioid Receptors under the supervision of prof. Javier Garzón. She carried out post-doctoral stays in Madrid (CNB), Germany (Würzburg University, supervisor Prof. Martin Lohse) and USA (Massachusetts General Hospital and Harvard Medical School, laboratory of prof. Jean-Pierre Vilardaga). Since 2012 she is Associate Professor of Pharmacology at the University of Santiago de Compostela, and head of the Research Group Molecular Pharmacology of G protein-coupled Receptors at the Center for Research in Molecular Medicine and Chronic Diseases (CIMUS) (University of Santiago de Compostela) and Research Staff at the Health Research Institute of Santiago de Compostela (IDIS). Her main research interest is the molecular, in vitro pharmacology of G protein-coupled receptors relevant in complex psychiatric illnesses. She studies the mechanisms of action of novel molecules active on these therapeutic targets and emerging aspects of GPCR intracellular signalling, by in vitro, cell-based studies. Her ultimate aim is to identify novel mechanisms of action for the pharmacological modulation of GPCR signalling and function in pathophysiological relevant cellular models.