Design, synthesis and medical evaluation of bioactive compounds and new materials
BICONMA
Centre National de la Recherche Scientifique
París, FranciaPublications in collaboration with researchers from Centre National de la Recherche Scientifique (9)
2023
2022
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Advances in Vitamin D Receptor Function and Evolution Based on the 3D Structure of the Lamprey Ligand-Binding Domain
Journal of Medicinal Chemistry, Vol. 65, Núm. 7, pp. 5821-5829
2021
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Design, Synthesis, Evaluation and Structure of Allenic 1α,25-Dihydroxyvitamin D3 Analogs with Locked Mobility at C-17
Chemistry - A European Journal, Vol. 27, Núm. 53, pp. 13384-13389
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Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR)
Bioorganic Chemistry, Vol. 115
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Lithocholic acid-based design of noncalcemic vitamin D receptor agonists
Bioorganic Chemistry, Vol. 111
2011
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1α,25(OH)2-3-epi-vitamin D3, a natural physiological metabolite of vitamin D3: Its synthesis, biological activity and crystal structure with its receptor
PLoS ONE, Vol. 6, Núm. 3
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Synthesis, structure, and biological activity of des-side Chain analogues of 1α,25-Dihydroxyvitamin D3 with substituents at C18
ChemMedChem, Vol. 6, Núm. 5, pp. 788-793
2008
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Structure-Based Design of a Superagonist Ligand for the Vitamin D Nuclear Receptor
Chemistry and Biology, Vol. 15, Núm. 4, pp. 383-392
2007
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Crystal structure of the vitamin D nuclear receptor ligand binding domain in complex with a locked side chain analog of calcitriol
Archives of Biochemistry and Biophysics, Vol. 460, Núm. 2, pp. 172-176