Farma SNC-EO
Farmacoloxía do Sistema Nervioso Central e do Estrés Oxidativo
Publicacións (29) Publicacións nas que participase algún/ha investigador/a
2024
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Gamma-Decanolactone Increases Stress Resistance and Improves Toxicity Parameters on the Caenorhabditis elegans Alternative Model
Journal of Applied Toxicology
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Toxicological assessment of the Achyrocline satureioides aqueous extract in the Caenorhabditis elegans alternative model
Journal of Toxicology and Environmental Health - Part A: Current Issues, Vol. 87, Núm. 18, pp. 730-751
2023
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8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies
European Journal of Medicinal Chemistry, Vol. 248
2021
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Gamma-decanolactone: Preliminary evaluation as potential antiparkinsonian drug
European Journal of Pharmacology, Vol. 906
2020
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Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies
Bioorganic Chemistry, Vol. 101
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Gamma-decanolactone attenuates acute and chronic seizures in mice: a possible role of adenosine A1 receptors
Behavioural pharmacology, Vol. 31, Núm. 6, pp. 544-552
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Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson's disease therapy
Bioorganic Chemistry, Vol. 104
2018
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Alkaloids as MAO-A inhibitors: Towards the final solution for depression and anxiety
Psychiatric and Mood Diseases and the Natural Compounds: An Approach to the Future Medical Tool (Nova Science Publishers, Inc.), pp. 169-192
2017
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Aporphine alkaloids and their antioxidant medical application: From antineoplastic agents to motor dysfunction diseases
Current Organic Chemistry, Vol. 21, Núm. 4, pp. 342-347
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MAO inhibitory activity of bromo-2-phenylbenzofurans: Synthesis,: in vitro study, and docking calculations
MedChemComm, Vol. 8, Núm. 9, pp. 1788-1796
2016
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Neuropharmacological effects of the ethanolic extract of Sida acuta
Brazilian Journal of Pharmacognosy, Vol. 26, Núm. 2, pp. 209-215
2015
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Anxiolytic-like effects of 7H-benzo[e]perimidin-7-one derivatives through elevated plus-maze test in mice
Current Topics in Medicinal Chemistry, Vol. 15, Núm. 17, pp. 1750-1754
2014
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Comparison of the antidepressive effects of trans-resveratrol and 5-methoxy-7H-dibenzo[de,h]quinolin-7-one.
Current topics in medicinal chemistry, Vol. 14, Núm. 2, pp. 234-238
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Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases
Future Medicinal Chemistry, Vol. 6, Núm. 4, pp. 371-383
2013
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Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: Synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study
European Journal of Medicinal Chemistry, Vol. 63, pp. 151-161
2012
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Calcium binding proteins
Advances in Experimental Medicine and Biology, Vol. 740, pp. 461-482
2010
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Vascular pro-oxidant effects secondary to the autoxidation of gallic acid in rat aorta
Journal of Nutritional Biochemistry, Vol. 21, Núm. 4, pp. 304-309
2009
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Vascular pro-oxidant effects related to the autoxication of dopamine
Free Radical Research, Vol. 43, Núm. 3, pp. 295-303
2008
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ANXIOLYTIC/HYPNOTIC AND MIORRELAXANT ACTIVITIES OF AZEPINE DERIVATIVES
METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
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HOMOCYSTINE-INDUCED DAMAGE IN DOPAMINERGIC NIGROSTRIATAL PATHWAYS
METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY