Grupo de Neurobioloxia Molecular e Celular da Enfermidade de Parkinson
Parkinson neurobiol
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Université de Genève
Ginebra, SuizaPublicacións en colaboración con investigadores/as de Université de Genève (2)
2015
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Structure-Based Design and Optimization of Multitarget-Directed 2 H -Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases
Journal of Medicinal Chemistry, Vol. 58, Núm. 14, pp. 5561-5578
2009
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Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: Development and biopharmacological profiling of 7-[(3-chlorobenzyl) oxy]-4-[(methylamino)methyl]-2H-chromen-2-one methanesulfonate (NW-1772) as a highly potent, selective, reversible, and orally active monoamine oxidase B inhibitor
Journal of Medicinal Chemistry, Vol. 52, Núm. 21, pp. 6685-6706