Engineering smart biomimetic nanocarriers for biomedical applications

  1. Migliavacca, Martina
Dirixida por:
  1. Ester Polo Tobajas Director
  2. Beatriz Pelaz García Director

Universidade de defensa: Universidade de Santiago de Compostela

Fecha de defensa: 10 de novembro de 2023

Tribunal:
  1. María Valeria Grazú Bonavía Presidente/a
  2. Patricia Díaz Rodríguez Secretario/a
  3. María Concepción Martínez-Esparza Alvargonzález Vogal
Departamento:
  1. Departamento de Química Inorgánica

Tipo: Tese

Resumo

The experimental results presented in this Doctoral Thesis shed light on the versatility and promising potential of cell-derived nanovesicles as a novel platform for addressing key challenges in modern medicine, ranging from targeted drug delivery to gene therapy. The exploration of cellsomes' biomimetic properties has demonstrated their capacity as innovative nanocarriers for molecules and drugs, as well as advanced biomimetic coating for other types of nanoparticles, capitalizing both on their tissue-specific targeting capabilities and on the possibility to engineer these nanocarriers to enhance the intracellular delivery.