Engineering smart biomimetic nanocarriers for biomedical applications
- Migliavacca, Martina
- Ester Polo Tobajas Director
- Beatriz Pelaz García Director
Universidade de defensa: Universidade de Santiago de Compostela
Fecha de defensa: 10 de novembro de 2023
- María Valeria Grazú Bonavía Presidente/a
- Patricia Díaz Rodríguez Secretario/a
- María Concepción Martínez Esparza Alvargonzález Vogal
Tipo: Tese
Resumo
The experimental results presented in this Doctoral Thesis shed light on the versatility and promising potential of cell-derived nanovesicles as a novel platform for addressing key challenges in modern medicine, ranging from targeted drug delivery to gene therapy. The exploration of cellsomes' biomimetic properties has demonstrated their capacity as innovative nanocarriers for molecules and drugs, as well as advanced biomimetic coating for other types of nanoparticles, capitalizing both on their tissue-specific targeting capabilities and on the possibility to engineer these nanocarriers to enhance the intracellular delivery.