Engineering smart biomimetic nanocarriers for biomedical applications

  1. Migliavacca, Martina
Supervised by:
  1. Ester Polo Tobajas Director
  2. Beatriz Pelaz García Director

Defence university: Universidade de Santiago de Compostela

Fecha de defensa: 10 November 2023

Committee:
  1. María Valeria Grazú Bonavía Chair
  2. Patricia Díaz Rodríguez Secretary
  3. María Concepción Martínez-Esparza Alvargonzález Committee member
Department:
  1. Department of Inorganic Chemistry

Type: Thesis

Abstract

The experimental results presented in this Doctoral Thesis shed light on the versatility and promising potential of cell-derived nanovesicles as a novel platform for addressing key challenges in modern medicine, ranging from targeted drug delivery to gene therapy. The exploration of cellsomes' biomimetic properties has demonstrated their capacity as innovative nanocarriers for molecules and drugs, as well as advanced biomimetic coating for other types of nanoparticles, capitalizing both on their tissue-specific targeting capabilities and on the possibility to engineer these nanocarriers to enhance the intracellular delivery.