Multi-state models for biomedical researchnew contributions in statistical modelling, software development, and applications.
- Meira Machado, Luís
- Carmen María Cadarso Suárez Director
- Jacobo de Uña Álvarez Director
Defence university: Universidade de Santiago de Compostela
Fecha de defensa: 01 December 2005
- Wenceslao González Manteiga Chair
- María del Carmen Iglesias Pérez Secretary
- Ingrid Van Keilegom Committee member
- Andersen Per Kragh Committee member
- Winfried Stute Committee member
Type: Thesis
Abstract
This thesis contains some co ntributions for statistical models studying the disease progression. Methods developed in this thesis are largely motivated by the applications to the medical sciences. Disease progression can be well described using multi-state models. These models may be considered as a generalization of the survival process where several (intermediate) events occur successively over time. Multi-state models offer a better understanding of the process of the illness, leading to a better knowledge of the evolution of the disease over time.