Molecular Medicine and Chronic Diseases Research Center (CIMUS)
Singular centre
Instituto de Investigación Sanitaria Biocruces Bizkaia
Barakaldo, EspañaPublications in collaboration with researchers from Instituto de Investigación Sanitaria Biocruces Bizkaia (24)
2024
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PLGA-PEI nanoparticle covered with poly(I:C) for personalised cancer immunotherapy
Drug Delivery and Translational Research
2023
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A second update on mapping the human genetic architecture of COVID-19
Nature
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Expanding the roles of the renin–angiotensin system: Drug-induced liver injury
Journal of Hepatology
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Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Cell Metabolism, Vol. 35, Núm. 8, pp. 1373-1389.e8
2022
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Angiocrine polyamine production regulates adiposity
Nature Metabolism, Vol. 4, Núm. 3, pp. 327-343
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Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
Journal of Hepatology, Vol. 76, Núm. 1, pp. 11-24
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Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis
Nature Communications, Vol. 13, Núm. 1
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Novel genes and sex differences in COVID-19 severity
Human molecular genetics, Vol. 31, Núm. 22, pp. 3789-3806
2021
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E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment
Cancer Research, Vol. 81, Núm. 11, pp. 2874-2887
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Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH
Journal of Hepatology, Vol. 75, Núm. 1, pp. 34-45
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Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis
Molecular Metabolism, Vol. 53
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The L-α-Lysophosphatidylinositol/G Protein–Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis
Hepatology, Vol. 73, Núm. 2, pp. 606-624
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The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant
Nature Genetics, Vol. 53, Núm. 10, pp. 1405-1414
2020
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Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease
Aging Cell, Vol. 19, Núm. 8
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Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly
Cell Metabolism, Vol. 31, Núm. 3, pp. 605-622.e10
2019
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SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer
EBioMedicine, Vol. 40, pp. 406-421
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miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease
Molecular Metabolism, Vol. 29, pp. 40-54
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p107 Deficiency Increases Energy Expenditure by Inducing Brown-Fat Thermogenesis and Browning of White Adipose Tissue
Molecular Nutrition and Food Research, Vol. 63, Núm. 2
2017
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A morphological method for ammonia detection in liver
PLoS ONE, Vol. 12, Núm. 3
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Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Nature Genetics, Vol. 49, Núm. 12, pp. 1767-1778