Centro de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS)
Centro singular
Helmholtz Zentrum München
Múnich, AlemaniaPublicacións en colaboración con investigadores/as de Helmholtz Zentrum München (34)
2023
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A second update on mapping the human genetic architecture of COVID-19
Nature
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Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1
Cell Metabolism, Vol. 35, Núm. 3, pp. 438-455.e7
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Gut hormone co-agonists for the treatment of obesity: from bench to bedside
Nature Metabolism, Vol. 5, Núm. 6, pp. 933-944
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Gut hormone-based pharmacology: novel formulations and future possibilities for metabolic disease therapy
Diabetologia, Vol. 66, Núm. 10, pp. 1796-1808
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High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling
Cell Reports, Vol. 42, Núm. 10
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Neuronal Blockade of Thyroid Hormone Signaling Increases Sensitivity to Diet-Induced Obesity in Adult Male Mice
Endocrinology (United States), Vol. 164, Núm. 4
2022
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An updated view on human neonatal thermogenesis
Nature Reviews Endocrinology
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Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner
GLIA, Vol. 70, Núm. 11, pp. 2062-2078
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Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency
Brain : a journal of neurology, Vol. 145, Núm. 12, pp. 4264-4274
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Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2-Dependent Mitotic Cell Death
Advanced Science, Vol. 9, Núm. 29
2021
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Divide et impera: How mitochondrial fission in astrocytes rules obesity
Molecular Metabolism
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Hypothalamic astrocytes as a specialized and responsive cell population in obesity
International Journal of Molecular Sciences, Vol. 22, Núm. 12
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Insulin action on astrocytes: From energy homeostasis to behaviour
Journal of Neuroendocrinology, Vol. 33, Núm. 4
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Is LRP2 involved in leptin transport over the blood-brain barrier and development of obesity?
International Journal of Molecular Sciences, Vol. 22, Núm. 9
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Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases
Nature Medicine, Vol. 27, Núm. 9, pp. 1564-1575
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O-GlcNAcylated p53 in the liver modulates hepatic glucose production
Nature Communications, Vol. 12, Núm. 1
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Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation
Nature Metabolism, Vol. 3, Núm. 10, pp. 1415-1431
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Synaptotagmin-13 is a neuroendocrine marker in brain, intestine and pancreas
International Journal of Molecular Sciences, Vol. 22, Núm. 22
2020
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HYPOTHesizing about central comBAT against obesity
Journal of Physiology and Biochemistry, Vol. 76, Núm. 2, pp. 193-211
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Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity
Journal of Clinical Investigation, Vol. 130, Núm. 11, pp. 6093-6108