Centro de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS)
Centro singular
Universidad Autónoma de Chile
Temuco, ChilePublicacións en colaboración con investigadores/as de Universidad Autónoma de Chile (18)
2024
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Unveiling the Significance of HLA and KIR Diversity in Underrepresented Populations
Biomedicines, Vol. 12, Núm. 6
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Utility of polygenic risk scores to aid in the diagnosis of rheumatic diseases
Best Practice and Research: Clinical Rheumatology
2023
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8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies
European Journal of Medicinal Chemistry, Vol. 248
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HLA alleles: important pieces to the COVID-19 puzzle
Trends in Immunology
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HLA-A*11:01 and HLA-C*04:01 are associated with severe COVID-19
HLA, Vol. 102, Núm. 6, pp. 731-739
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Phytochemical Analysis and Antiproliferative Activity of Ulex gallii Planch. (Fabaceae), a Medicinal Plant from Galicia (Spain)
Molecules, Vol. 28, Núm. 1
2022
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Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin
Molecules, Vol. 27, Núm. 3
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Synthesis and Vasorelaxant Activity of Nitrate−Coumarin Derivatives
ChemMedChem, Vol. 17, Núm. 21
2021
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7-Amidocoumarins as Multitarget Agents against Neurodegenerative Diseases: Substitution Pattern Modulation
ChemMedChem, Vol. 16, Núm. 1, pp. 179-186
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Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors
Bioorganic Chemistry, Vol. 108
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Curcumin–coumarin hybrid analogues as multitarget agents in neurodegenerative disorders
Molecules, Vol. 26, Núm. 15
2020
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3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?
Bioorganic Chemistry, Vol. 101
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Coumarin-Rasagiline Hybrids as Potent and Selective hMAO-B Inhibitors, Antioxidants, and Neuroprotective Agents
ChemMedChem, Vol. 15, Núm. 6, pp. 532-538
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Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies
Bioorganic Chemistry, Vol. 101
2019
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Design, Synthesis and Docking Calculations of Prenylated Chalcones as Selective Monoamine Oxidase B Inhibitors with Antioxidant Activity
ChemistrySelect, Vol. 4, Núm. 26, pp. 7698-7703
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Discovery of new phthalazinones as vasodilator agents and novel pharmacological tools to study calcium channels
Future Medicinal Chemistry, Vol. 11, Núm. 3, pp. 179-191
2017
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Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors
European Journal of Medicinal Chemistry, Vol. 139, pp. 1-11
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Synthesis and vasorelaxant and antiplatelet activities of a new series of (4-Benzylphthalazin-1-ylamino)alcohol derivatives
Medicinal Chemistry Research, Vol. 26, Núm. 8, pp. 1682-1688