Instituto de Materiais
Instituto
![Foto de Miguel](/img/nophoto.png)
Miguel
Maestro
Publicacións nas que colabora con Miguel Maestro (37)
2023
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Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3 (Calcitriol): Refinement of the Side Chain
Journal of Medicinal Chemistry, Vol. 66, Núm. 22, pp. 15326-15339
2022
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Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3
Journal of Medicinal Chemistry, Vol. 65, Núm. 19, pp. 13112-13124
2021
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Design, Synthesis, Evaluation and Structure of Allenic 1α,25-Dihydroxyvitamin D3 Analogs with Locked Mobility at C-17
Chemistry - A European Journal, Vol. 27, Núm. 53, pp. 13384-13389
2019
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Synthesis of 28,28,28-trideutero-25-hydroxydihydrotachysterol 2
Journal of Steroid Biochemistry and Molecular Biology, Vol. 185, pp. 248-250
2018
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Total synthesis of 1α,25-dihydroxyvitamin D
3
analogs modified at the side chain and D-ring
Organic and Biomolecular Chemistry, Vol. 16, Núm. 24, pp. 4563-4569
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Stereoselective synthesis of 25S,26-dihydroxyvitamin D 3
Journal of Steroid Biochemistry and Molecular Biology, Vol. 177, pp. 247-249
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Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists
Journal of Medicinal Chemistry, Vol. 61, Núm. 11, pp. 4928-4937
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Stereoselective Palladium-Catalyzed Approach to Vitamin D3 Derivatives in Protic Medium
Chemistry - A European Journal, Vol. 24, Núm. 13, pp. 3314-3320
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Synthesis of Side-Chain Locked Analogs of 1α,25-Dihydroxyvitamin D3 Bearing a C17 Methyl Group
Organic Letters, Vol. 20, Núm. 9, pp. 2641-2644
2017
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A new approach to 19-nor-A-ring phosphine oxide for the convergent synthesis of 19-nor-calcitriol
Journal of Steroid Biochemistry and Molecular Biology, Vol. 173, pp. 86-88
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Total synthesis of 1α,25-dihydroxyvitamin D3 (calcitriol) through a Si-assisted allylic substitution
Chemical Communications, Vol. 53, Núm. 58, pp. 8144-8147
2016
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Carborane-based design of a potent Vitamin D receptor agonist
Chemical Science, Vol. 7, Núm. 2, pp. 1033-1037
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Stereoselective synthesis of 1β,25-Dihydroxyvitamin D3 and its 26,27-hexadeuterated derivative
Journal of Steroid Biochemistry and Molecular Biology, Vol. 164, pp. 56-58
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Vitamin D receptor 2016: novel ligands and structural insights
Expert Opinion on Therapeutic Patents, Vol. 26, Núm. 11, pp. 1291-1306
2015
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An efficient convergent synthesis of 1α,25-dihydroxy-3-epi-vitamin D2
Journal of Steroid Biochemistry and Molecular Biology, Vol. 148, pp. 31-33
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Pit-1 inhibits BRCA1 and sensitizes human breast tumors to cisplatin and vitamin D treatment
Oncotarget, Vol. 6, Núm. 16, pp. 14456-14471
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Quantitative analytical method to evaluate the metabolism of vitamin D
Clinica Chimica Acta, Vol. 442, pp. 6-12
2014
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26,26,26,27,27,27-hexadeuterated-1,25-dihydroxyvitamin D3 (1,25D-d6) as adjuvant of chemotherapy in breast cancer cell lines
Cancers, Vol. 6, Núm. 1, pp. 67-78
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Clinical utility of simultaneous quantitation of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D by LC-MS/MS involving derivatization with DMEQ-TAD
Journal of Clinical Endocrinology and Metabolism, Vol. 99, Núm. 7, pp. 2567-2574
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Synthesis of nonadeuterated 1α,25-dihydroxyvitamin D2
Journal of Steroid Biochemistry and Molecular Biology, Vol. 144, Núm. PART A, pp. 204-206