Publications by the researcher in collaboration with Manuel José Tena Sempere (81)

2022

  1. Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway

    International Journal of Molecular Sciences, Vol. 23, Núm. 6

2021

  1. AMP-activated protein kinase (AMPK) signaling in GnRH neurons links energy status and reproduction

    Metabolism: Clinical and Experimental, Vol. 115

  2. Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation

    Nature Metabolism, Vol. 3, Núm. 10, pp. 1415-1431

2020

  1. AMPK-Dependent Mechanisms but Not Hypothalamic Lipid Signaling Mediates GH-Secretory Responses to GHRH and Ghrelin

    Cells, Vol. 9, Núm. 9

  2. Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty

    Cell Metabolism, Vol. 32, Núm. 6, pp. 951-966.e8

2018

  1. Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress

    Cell Reports, Vol. 25, Núm. 2, pp. 413-423.e5

  2. Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Núm. 45, pp. E10758-E10767

  3. SF1-specific AMPKa1 deletion protects against diet-induced obesity

    Diabetes, Vol. 67, Núm. 11, pp. 2213-2226

  4. SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression

    Nature Communications, Vol. 9, Núm. 1

  5. Sex-Biased Physiological Roles of NPFF1R, the Canonical Receptor of RFRP-3, in Food Intake and Metabolic Homeostasis Revealed by its Congenital Ablation in mice

    Metabolism: Clinical and Experimental, Vol. 87, pp. 87-97

  6. mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol

    Journal of Endocrinology, Vol. 238, Núm. 3, pp. 177-186

2017

  1. Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance

    Cell Metabolism, Vol. 26, Núm. 1, pp. 212-229.e12

  2. Reduction of hypothalamic endoplasmic reticulum stress activates browning of white fat and ameliorates obesity

    Diabetes, Vol. 66, Núm. 1, pp. 87-99

  3. Sequential Exposure to Obesogenic Factors in Females Rats: From Physiological Changes to Lipid Metabolism in Liver and Mesenteric Adipose Tissue

    Scientific Reports, Vol. 7

2016

  1. A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance

    Cell Reports, Vol. 16, Núm. 8, pp. 2231-2242

  2. Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty

    Molecular Metabolism, Vol. 5, Núm. 10, pp. 844-857

  3. Hypothalamic AMPK: A canonical regulator of whole-body energy balance

    Nature Reviews Endocrinology, Vol. 12, Núm. 7, pp. 421-432

2015

  1. Metabolic and gonadotropic impact of sequential obesogenic insults in the female: Influence of the loss of ovarian secretion

    Endocrinology, Vol. 156, Núm. 8, pp. 2984-2998

  2. Orexins (hypocretins) and energy balance: More than feeding

    Molecular and Cellular Endocrinology, Vol. 418, pp. 17-26

  3. Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-COA and the thermogenic effect of hypothalamic AMPK inhibition in female rats

    Endocrinology, Vol. 156, Núm. 3, pp. 947-960