Publikationen in Zusammenarbeit mit Forschern von Uppsala University (23)

2023

  1. Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia

    Molecules, Vol. 28, Núm. 10

2022

  1. A 2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models

    Journal for ImmunoTherapy of Cancer, Vol. 10, Núm. 5

  2. Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat

    ACS Nano, Vol. 16, Núm. 9, pp. 14210-14229

  3. Exploring Non-orthosteric Interactions with a Series of Potent and Selective A3Antagonists

    ACS Medicinal Chemistry Letters, Vol. 13, Núm. 2, pp. 243-249

  4. Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1Antagonists

    Journal of Medicinal Chemistry, Vol. 65, Núm. 3, pp. 2091-2106

2021

  1. 3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition

    Journal of medicinal chemistry, Vol. 64, Núm. 1, pp. 458-480

  2. Deciphering conformational selectivity in the A2A adenosine G protein-coupled receptor by free energy simulations

    PLoS Computational Biology, Vol. 17, Núm. 11

  3. Identification of V6.51L as a selectivity hotspot in stereoselective A2B adenosine receptor antagonist recognition

    Scientific Reports, Vol. 11, Núm. 1

  4. Potent and Subtype-Selective Dopamine D2Receptor Biased Partial Agonists Discovered via an Ugi-Based Approach

    Journal of Medicinal Chemistry, Vol. 64, Núm. 12, pp. 8710-8726

  5. Structure-Guided Design of G-Protein-Coupled Receptor Polypharmacology

    Angewandte Chemie - International Edition, Vol. 60, Núm. 33, pp. 18022-18030

2020

  1. Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A2B Adenosine Receptor Antagonists

    Journal of medicinal chemistry, Vol. 63, Núm. 14, pp. 7721-7739

  2. The European Research Network on Signal Transduction (ERNEST): Toward a Multidimensional Holistic Understanding of G Protein-Coupled Receptor Signaling

    ACS Pharmacology and Translational Science, Vol. 3, Núm. 2, pp. 361-370

  3. WSV 2019: The First Committee Meeting of the World Society for Virology

    Virologica Sinica, Vol. 35, Núm. 2, pp. 248-252

2019

  1. Free-Energy calculations for bioisosteric modifications of A3adenosine receptor antagonists

    International Journal of Molecular Sciences, Vol. 20, Núm. 14

  2. Trifluorinated Pyrimidine-Based A2B Antagonists: Optimization and Evidence of Stereospecific Recognition

    Journal of Medicinal Chemistry, Vol. 62, Núm. 20, pp. 9315-9330

2018

  1. The stimulation of GLP-1 secretion and delivery of GLP-1 agonists: Via nanostructured lipid carriers

    Nanoscale, Vol. 10, Núm. 2, pp. 603-613

2017

  1. 3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation

    ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933

  2. Effect of Nitrogen Atom Substitution in A3 Adenosine Receptor Binding: N-(4,6-Diarylpyridin-2-yl)acetamides as Potent and Selective Antagonists

    Journal of Medicinal Chemistry, Vol. 60, Núm. 17, pp. 7502-7511

  3. Enantiospecific Recognition at the A2B Adenosine Receptor by Alkyl 2-Cyanoimino-4-substituted-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylates

    Journal of Medicinal Chemistry, Vol. 60, Núm. 8, pp. 3372-3382

2016

  1. Combining ligand-based and structure-based ligand design towards the development of potent and selective antagonists for the adenosine receptors

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY