Facultade de Farmacia
Facultad
University of Würzburg
Wurzburgo, AlemaniaPublicacións en colaboración con investigadores/as de University of Würzburg (16)
2021
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From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
European Journal of Medicinal Chemistry, Vol. 225
2020
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Adenosine receptor ligands: Coumarin–Chalcone hybrids as modulating agents on the activity of hARs
Molecules, Vol. 25, Núm. 18
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Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists
Journal of Medicinal Chemistry, Vol. 63, Núm. 5, pp. 2577-2587
2018
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Coumarins and adenosine receptors: New perceptions in structure–affinity relationships
Chemical Biology and Drug Design, Vol. 91, Núm. 1, pp. 245-256
2016
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Progress in the development of small molecules as new human A3 adenosine receptor ligands based on the 3-thiophenylcoumarin core
MedChemComm, Vol. 7, Núm. 5, pp. 845-852
2015
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Development of novel adenosine receptor ligands based on the 3-amidocoumarin scaffold
Bioorganic Chemistry, Vol. 61, pp. 1-6
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Ligand residence time at G-protein-coupled receptors - Why we should take our time to study it
Molecular Pharmacology, Vol. 88, Núm. 3, pp. 552-560
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Navigating in chromone chemical space: Discovery of novel and distinct A3 adenosine receptor ligands
RSC Advances, Vol. 5, Núm. 96, pp. 78572-78585
2013
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Chalcone-based derivatives as new scaffolds for hA3 adenosine receptor antagonists
Journal of Pharmacy and Pharmacology, Vol. 65, Núm. 5, pp. 697-703
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Synthesis and adenosine receptors binding affinities of a series of 3-arylcoumarins
Journal of Pharmacy and Pharmacology, Vol. 65, Núm. 11, pp. 1590-1597
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Targeting adenosine receptors with coumarins: Synthesis and binding activities of amide and carbamate derivatives
Journal of Pharmacy and Pharmacology, Vol. 65, Núm. 1, pp. 30-34
2012
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Discovery of novel A 3 adenosine receptor ligands based on chromone scaffold
Biochemical Pharmacology, Vol. 84, Núm. 1, pp. 21-29
2005
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Human breast cancer cell line MDA-MB-231 expresses endogenous A 2B adenosine receptors mediating a Ca 2+ signal
British Journal of Pharmacology, Vol. 145, Núm. 2, pp. 211-218
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Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism
Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Núm. 44, pp. 16084-16089
2003
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Measurement of the millisecond activation switch of G protein-coupled receptors in living cells
Nature Biotechnology, Vol. 21, Núm. 7, pp. 807-812
2002
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Dual regulation of the parathyroid hormone (PTH)/PTH-related peptide receptor signaling by protein kinase C and β-arrestins
Endocrinology, Vol. 143, Núm. 10, pp. 3854-3865