Department of Organic chemistry
Department
University of Bari Aldo Moro
Bari, ItaliaPublications in collaboration with researchers from University of Bari Aldo Moro (18)
2024
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N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)
Journal of Medicinal Chemistry, Vol. 67, Núm. 13, pp. 11003-11023
2023
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Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase
Journal of Medicinal Chemistry, Vol. 66, Núm. 1, pp. 235-250
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Fluorescence based HTS-compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells
Frontiers in Molecular Biosciences, Vol. 10
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Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs
International Journal of Molecular Sciences, Vol. 24, Núm. 7
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N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R)
European Journal of Medicinal Chemistry, Vol. 248
2022
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Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase
Separations, Vol. 9, Núm. 1
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Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1Antagonists
Journal of Medicinal Chemistry, Vol. 65, Núm. 3, pp. 2091-2106
2021
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3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition
Journal of medicinal chemistry, Vol. 64, Núm. 1, pp. 458-480
2016
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8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease
ChemistrySelect, Vol. 1, Núm. 11, pp. 2742-2749
2015
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Computer-aided structure-based design of multitarget leads for Alzheimer's disease
Journal of Chemical Information and Modeling, Vol. 55, Núm. 1, pp. 135-148
2009
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1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships
Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 10, pp. 3618-3629
2008
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1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor
Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 6, pp. 2852-2869
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Corrigendum to "1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor" [Bioorg. Med. Chem. 16 (2008) 2852-2869] (DOI:10.1016/j.bmc.2008.01.002)
Bioorganic and Medicinal Chemistry
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Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ1-40 aggregation in vitro
Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 9, pp. 4810-4822
2006
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Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor
Journal of Medicinal Chemistry, Vol. 49, Núm. 1, pp. 282-299
2004
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8-Substituted-9-deazaxanthines as adenosine receptor ligands: Design, synthesis and structure-affinity relationships at A 2B
European Journal of Medicinal Chemistry, Vol. 39, Núm. 10, pp. 879-887
2002
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New serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonists: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones
Journal of Medicinal Chemistry, Vol. 45, Núm. 1, pp. 54-71
1999
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Conformationally constrained butyrophenones with mixed dopaminergic (D2) and serotoninergic (5-HT2(A), 5-HT2(C)) affinities: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and - thienocycloalkanones as putative atypical antipsychotics
Journal of Medicinal Chemistry, Vol. 42, Núm. 15, pp. 2774-2797