Departamento de Química Orgánica
Departamento
Universidade Do Porto
Oporto, PortugalPublicacións en colaboración con investigadores/as de Universidade Do Porto (185)
2024
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Discovery of hybrid Glypromate conjugates with neuroprotective activity against paraquat-induced toxicity
RSC Medicinal Chemistry
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Exploring structural determinants of neuroprotection bias on novel glypromate conjugates with bioactive amines
European Journal of Medicinal Chemistry, Vol. 267
2023
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2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 38, Núm. 1
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8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies
European Journal of Medicinal Chemistry, Vol. 248
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Concise Overview of Glypromate Neuropeptide Research: From Chemistry to Pharmacological Applications in Neurosciences
ACS Chemical Neuroscience, Vol. 14, Núm. 4, pp. 554-572
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Cytogenotoxicity assessment of 3-(3,4-dihydroxyphenyl)-7,8-dihydroxycoumarin on HepG2/C3A cells and leukocytes
Journal of Applied Toxicology, Vol. 43, Núm. 2, pp. 323-334
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In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies
Journal of Biomolecular Structure and Dynamics, Vol. 41, Núm. 22, pp. 13250-13259
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Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks
Journal of Medicinal Chemistry, Vol. 66, Núm. 3, pp. 1835-1851
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Oxidation-labile linkers for controlled drug delivery
Bioorganic and Medicinal Chemistry Letters, Vol. 87
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Phytochemical Analysis and Antiproliferative Activity of Ulex gallii Planch. (Fabaceae), a Medicinal Plant from Galicia (Spain)
Molecules, Vol. 28, Núm. 1
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Propargylamine: an important moiety in drug discovery
Future Medicinal Chemistry, Vol. 15, Núm. 1, pp. 211-224
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Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D2 Receptors
ACS Medicinal Chemistry Letters, Vol. 14, Núm. 12, pp. 1656-1663
2022
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A comprehensive ethnobotanical profile of Ocimum campechianum (Lamiaceae): from traditional medicine to phytochemical and pharmacological evidences
Plant Biosystems, Vol. 156, Núm. 6, pp. 1388-1404
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Corrigendum to “pH-regulated interaction modes between cyanidin-3-glucoside and phenylboronic acid-modified alginate” [Carbohydr. Polym. 280 (2022) 119029] (Carbohydrate Polymers (2022) 280, (S0144861721014168), (10.1016/j.carbpol.2021.119029))
Carbohydrate Polymers
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Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin
Molecules, Vol. 27, Núm. 3
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Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties
European Journal of Medicinal Chemistry, Vol. 239
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Isolation and structural characterization of stable carbamic-carbonic anhydrides: an experimental and computational study
Organic Chemistry Frontiers, Vol. 9, Núm. 8, pp. 2154-2163
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Molecular Dynamics Simulations of Transmembrane Cyclic Peptide Nanotubes Using Classical Force Fields, Hydrogen Mass Repartitioning, and Hydrogen Isotope Exchange Methods: A Critical Comparison
International Journal of Molecular Sciences, Vol. 23, Núm. 6
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Partition of antimicrobial D-L-α-cyclic peptides into bacterial model membranes
Biochimica et Biophysica Acta - Biomembranes, Vol. 1864, Núm. 1
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SuPepMem: A database of innate immune system peptides and their cell membrane interactions
Computational and Structural Biotechnology Journal, Vol. 20, pp. 874-881