Departamento de Química Orgánica
Departamento
University of Cambridge
Cambridge, Reino UnidoPublicaciones en colaboración con investigadores/as de University of Cambridge (55)
2023
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Low Oxidation State Cobalt Center Stabilized by a Covalent Organic Framework to Promote Hydroboration of Olefins
ACS Catalysis, Vol. 13, Núm. 5, pp. 3044-3054
2022
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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry
Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294
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Visible-Light-Mediated Modification and Manipulation of Biomacromolecules
Chemical Reviews, Vol. 122, Núm. 2, pp. 1752-1829
2020
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Activation of Copper Species on Carbon Nitride for Enhanced Activity in the Arylation of Amines
ACS Catalysis, Vol. 10, Núm. 19, pp. 11069-11080
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Catalytic C(sp 3)–H bond activation in tertiary alkylamines
Nature Chemistry, Vol. 12, Núm. 1, pp. 76-81
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Selective Chemical Functionalization at N6-Methyladenosine Residues in DNA Enabled by Visible-Light-Mediated Photoredox Catalysis
Journal of the American Chemical Society, Vol. 142, Núm. 51, pp. 21484-21492
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Sequential dual site-selective protein labelling enabled by lysine modification
Bioorganic and Medicinal Chemistry, Vol. 28, Núm. 22
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Spatially Controlled Supramolecular Polymerization of Peptide Nanotubes by Microfluidics
Angewandte Chemie - International Edition, Vol. 59, Núm. 17, pp. 6902-6908
2019
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A Class of N-O-Type Oxidants to Access High-Valent Palladium Species
Organometallics, Vol. 38, Núm. 1, pp. 143-148
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Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
Nature Protocols, Vol. 14, Núm. 1, pp. 86-99
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Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification
ACS Central Science, Vol. 5, Núm. 8, pp. 1417-1424
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Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent
Methods in Molecular Biology (Humana Press Inc.), pp. 25-37
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Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation
Angewandte Chemie - International Edition, Vol. 58, Núm. 20, pp. 6640-6644
2018
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A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis
Peptide Science, Vol. 110, Núm. 3
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A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging
Chemical Science, Vol. 9, Núm. 17, pp. 4185-4189
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Chemo- and Regioselective Lysine Modification on Native Proteins
Journal of the American Chemical Society, Vol. 140, Núm. 11, pp. 4004-4017
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Learning from nature: The role of albumin in drug delivery
Future Medicinal Chemistry
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Modulation of pore shape and adsorption selectivity by ligand functionalization in a series of "rob"-like flexible metal-organic frameworks
Journal of Materials Chemistry A, Vol. 6, Núm. 36, pp. 17409-17416
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Selective Reductive Elimination at Alkyl Palladium(IV) by Dissociative Ligand Ionization: Catalytic C(sp3)−H Amination to Azetidines
Angewandte Chemie - International Edition, Vol. 57, Núm. 12, pp. 3178-3182
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Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates
Chemistry - A European Journal, Vol. 24, Núm. 47, pp. 12250-12253