Departamento de Química Orgánica
Institut
Universidade de Coimbra
Coímbra, PortugalPublikationen in Zusammenarbeit mit Forschern von Universidade de Coimbra (14)
2024
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Gemcitabine-Vitamin E Prodrug-Loaded Micelles for Pancreatic Cancer Therapy
Pharmaceutics, Vol. 16, Núm. 1
2023
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Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks
Journal of Medicinal Chemistry, Vol. 66, Núm. 3, pp. 1835-1851
2022
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Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties
European Journal of Medicinal Chemistry, Vol. 239
2019
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Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents
European Journal of Medicinal Chemistry, Vol. 174, pp. 116-129
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Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction
European Journal of Medicinal Chemistry, Vol. 167, pp. 525-545
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Insights into the discovery of novel neuroprotective agents: A comparative study between sulfanylcinnamic acid derivatives and related phenolic analogues
Molecules, Vol. 24, Núm. 23
2018
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Hydroxybenzoic acid derivatives as dual-target ligands: Mitochondriotropic antioxidants and cholinesterase inhibitors
Frontiers in Chemistry, Vol. 6, Núm. APR
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Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors
European Journal of Medicinal Chemistry, Vol. 158, pp. 781-800
2014
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Synthesis and electrochemical study of new 3-(hydroxyphenyl)benzo[f] coumarins
Journal of Electroanalytical Chemistry, Vol. 726, pp. 62-70
2013
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Cholesterol and POPC segmental order parameters in lipid membranes: Solid state 1H-13C NMR and MD simulation studies
Physical Chemistry Chemical Physics, Vol. 15, Núm. 6, pp. 1976-1989
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New hydroxylated 3-arylcoumarins, synthesis and electrochemical study
Journal of Electroanalytical Chemistry, Vol. 689, pp. 243-251
2010
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New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors
Bioorganic and Medicinal Chemistry Letters, Vol. 20, Núm. 17, pp. 5157-5160
2008
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Segmental order parameters in a nonionic surfactant lamellar phase studied with 1H-13C solid-state NMR
Physical Chemistry Chemical Physics, Vol. 10, Núm. 39, pp. 6033-6038
2007
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Electrochemical and spectroscopic characterisation of amphetamine-like drugs: Application to the screening of 3,4-methylenedioxymethamphetamine (MDMA) and its synthetic precursors
Analytica Chimica Acta, Vol. 596, Núm. 2, pp. 231-241