Publicacións nas que colabora con MARIA MANEIRO REY (13)

2023

  1. Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme—A molecular insight †

    Frontiers in Molecular Biosciences, Vol. 10

2021

  1. 6-Halopyridylmethylidene Penicillin-Based Sulfones Efficiently Inactivate the Natural Resistance of Pseudomonas aeruginosa to β-Lactam Antibiotics

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 6310-6328

  2. Activity of imipenem, meropenem, cefepime, and sulbactam in combination with the β-lactamase inhibitor ln-1-255 against acinetobacter spp.

    Antibiotics, Vol. 10, Núm. 2, pp. 1-15

2020

  1. 6-Arylmethylidene Penicillin-Based Sulfone Inhibitors for Repurposing Antibiotic Efficiency in Priority Pathogens

    Journal of Medicinal Chemistry, Vol. 63, Núm. 7, pp. 3737-3755

  2. Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product

    Chemistry - A European Journal, Vol. 26, Núm. 36, pp. 8035-8044

2019

  1. Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme

    Organic Chemistry Frontiers, Vol. 6, Núm. 17, pp. 3127-3135

  2. Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii

    Antimicrobial Agents and Chemotherapy, Vol. 63, Núm. 10

2018

  1. Chemo- and Regioselective Lysine Modification on Native Proteins

    Journal of the American Chemical Society, Vol. 140, Núm. 11, pp. 4004-4017

  2. Nuevos inhibidores de enzimas implicados en la virulencia, el metabolismo y los mecanismos de resistencia de las bacterias para el tratamiento de las infecciones bacterianas multi-resistentes

    Nuevos inhibidores de enzimas implicados en la virulencia, el metabolismo y los mecanismos de resistencia de las bacterias para el tratamiento de las infecciones bacterianas multi-resistentes

2017

  1. Activity of the ß-Lactamase inhibitor LN-1-255 against carbapenem-hydrolyzing class D ß-Lactamases from acinetobacter baumannii

    Antimicrobial Agents and Chemotherapy, Vol. 61, Núm. 11

2016

  1. Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme

    Journal of Medicinal Chemistry, Vol. 59, Núm. 11, pp. 5471-5487

2015

  1. Irreversible covalent modification of type i dehydroquinase with a stable Schiff base

    Organic and Biomolecular Chemistry, Vol. 13, Núm. 3, pp. 706-716

2014

  1. Insights into substrate binding and catalysis in bacterial type i dehydroquinase

    Biochemical Journal, Vol. 462, Núm. 3, pp. 415-424