Department of Organic chemistry
Department
MARIA DOLORES
VIÑA CASTELAO
Senior university lecturer
Publications by the researcher in collaboration with MARIA DOLORES VIÑA CASTELAO (55)
2023
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8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies
European Journal of Medicinal Chemistry, Vol. 248
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Phytochemical Analysis and Antiproliferative Activity of Ulex gallii Planch. (Fabaceae), a Medicinal Plant from Galicia (Spain)
Molecules, Vol. 28, Núm. 1
2022
2021
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7-Amidocoumarins as Multitarget Agents against Neurodegenerative Diseases: Substitution Pattern Modulation
ChemMedChem, Vol. 16, Núm. 1, pp. 179-186
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Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors
Bioorganic Chemistry, Vol. 108
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Curcumin–coumarin hybrid analogues as multitarget agents in neurodegenerative disorders
Molecules, Vol. 26, Núm. 15
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Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)
ACS Chemical Neuroscience, Vol. 12, Núm. 1, pp. 203-215
2020
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3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?
Bioorganic Chemistry, Vol. 101
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Coumarin-Rasagiline Hybrids as Potent and Selective hMAO-B Inhibitors, Antioxidants, and Neuroprotective Agents
ChemMedChem, Vol. 15, Núm. 6, pp. 532-538
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Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies
Bioorganic Chemistry, Vol. 101
2019
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Design, Synthesis and Docking Calculations of Prenylated Chalcones as Selective Monoamine Oxidase B Inhibitors with Antioxidant Activity
ChemistrySelect, Vol. 4, Núm. 26, pp. 7698-7703
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Discovery of new phthalazinones as vasodilator agents and novel pharmacological tools to study calcium channels
Future Medicinal Chemistry, Vol. 11, Núm. 3, pp. 179-191
2018
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Novel 2-pheynlbenzofuran derivatives as selective butyrylcholinesterase inhibitors for Alzheimer's disease
Scientific Reports, Vol. 8, Núm. 1
2017
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MAO inhibitory activity of bromo-2-phenylbenzofurans: Synthesis,: in vitro study, and docking calculations
MedChemComm, Vol. 8, Núm. 9, pp. 1788-1796
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Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors
European Journal of Medicinal Chemistry, Vol. 139, pp. 1-11
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Synthesis and vasorelaxant and antiplatelet activities of a new series of (4-Benzylphthalazin-1-ylamino)alcohol derivatives
Medicinal Chemistry Research, Vol. 26, Núm. 8, pp. 1682-1688
2016
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Computational Drug Target Screening through Protein Interaction Profiles
Scientific Reports, Vol. 6
2015
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3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases
ChemMedChem, Vol. 10, Núm. 12, pp. 2071-2079
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Potent and selective MAO-B inhibitory activity: Amino- versus nitro-3-arylcoumarin derivatives
Bioorganic and Medicinal Chemistry Letters, Vol. 25, Núm. 3, pp. 642-648
2014
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Insight into the functional and structural properties of 3-arylcoumarin as an interesting scaffold in monoamine oxidase B inhibition
ChemMedChem, Vol. 9, Núm. 7, pp. 1488-1500