Departamento de Química Orgánica
Departamento
JOSE ANGEL
FONTENLA GIL
Profesor titular de universidad
Publicaciones en las que colabora con JOSE ANGEL FONTENLA GIL (23)
2023
-
8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies
European Journal of Medicinal Chemistry, Vol. 248
2020
2017
-
Aporphine alkaloids and their antioxidant medical application: From antineoplastic agents to motor dysfunction diseases
Current Organic Chemistry, Vol. 21, Núm. 4, pp. 342-347
-
MAO inhibitory activity of bromo-2-phenylbenzofurans: Synthesis,: in vitro study, and docking calculations
MedChemComm, Vol. 8, Núm. 9, pp. 1788-1796
2015
-
Anxiolytic-like effects of 7H-benzo[e]perimidin-7-one derivatives through elevated plus-maze test in mice
Current Topics in Medicinal Chemistry, Vol. 15, Núm. 17, pp. 1750-1754
2014
-
Comparison of the antidepressive effects of trans-resveratrol and 5-methoxy-7H-dibenzo[de,h]quinolin-7-one.
Current topics in medicinal chemistry, Vol. 14, Núm. 2, pp. 234-238
-
Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases
Future Medicinal Chemistry, Vol. 6, Núm. 4, pp. 371-383
2013
-
Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: Synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study
European Journal of Medicinal Chemistry, Vol. 63, pp. 151-161
2003
-
New arylpiperazine derivatives with high affinity for α1A, D2 and 5-HT2A receptors
Bioorganic and Medicinal Chemistry Letters, Vol. 13, Núm. 2, pp. 175-178
2000
-
Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: Synthesis and determination of affinities at D2, 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors
European Journal of Medicinal Chemistry, Vol. 35, Núm. 1, pp. 83-95
-
Conformationally constrained butyrophenones with affinity for dopamine (D1, D2, D4) and serotonin (5-HT(2A), 5-HT(2B), 5-HT(2C)) receptors: Synthesis of aminomethylbenzo[b]furanones and their evaluation as antipsychotics
Journal of Medicinal Chemistry, Vol. 43, Núm. 24, pp. 4678-4693
1999
-
Conformationally constrained butyrophenones with mixed dopaminergic (D2) and serotoninergic (5-HT2(A), 5-HT2(C)) affinities: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and - thienocycloalkanones as putative atypical antipsychotics
Journal of Medicinal Chemistry, Vol. 42, Núm. 15, pp. 2774-2797
1998
-
Butyrophenone analogues in the carbazole series: Synthesis and determination of affinities at D2 and 5-HT(2A) receptors
Bioorganic and Medicinal Chemistry Letters, Vol. 8, Núm. 24, pp. 3571-3576
1997
-
New cyclic butyrophenone derivatives in the indole series as potential atypical antipsychotics. A simple and practical synthesis of 6-aminomethyl-tetrahydroindol-4-ones and their affinities for D2 and 5-HT(2A) receptors
Bioorganic and Medicinal Chemistry Letters, Vol. 7, Núm. 7, pp. 913-918
1996
-
Synthesis and affinities for dopamine (D2) and 5-hydroxytryptamine (5-HT2A) receptors of 1-(benzoylpropyl)-4-(1-oxocycloalkyl-2-ethyl)-piperazines as cyclic butyrophenone derivatives
Chemical and Pharmaceutical Bulletin, Vol. 44, Núm. 3, pp. 534-541
1995
-
Butyrophenone analogues: Synthesis of 2-methyl-3-ethyl-5-aminoethyl-4,5,6,7-tetrahydroindol-4-ones, and their affinities for d 1 , d 2 and 5-ht 2a receptors
Bioorganic and Medicinal Chemistry Letters, Vol. 5, Núm. 6, pp. 579-584
1994
-
Pyridazine derivatives XII. Synthesis and antipsychotic-antidepressant activity of some butyrophenone derivatives of 6-phenylpyridazine
European Journal of Medicinal Chemistry, Vol. 29, Núm. 11, pp. 831-839
1993
-
Cyproheptadine analogues: Synthesis, antiserotoninergic activity, and structure‐activity relationships
Journal of Pharmaceutical Sciences, Vol. 82, Núm. 11, pp. 1090-1093
1991
-
Synthesis and Antidopaminergic Activity of Some 3-(Aminomethyl)tetralones as Analogues of Butyrophenone
Journal of Medicinal Chemistry, Vol. 34, Núm. 7, pp. 2242-2247
1989
-
Pyridazine Derivatives, VII. Synthesis and Hypotensive Activity of 3‐Hydrazinocycloalkyl[1,2‐c]pyridazines and their Derivatives
Archiv der Pharmazie, Vol. 322, Núm. 6, pp. 331-336