Publications by the researcher in collaboration with MARIA ISABEL CADAVID TORRES (20)

2017

  1. Effect of Nitrogen Atom Substitution in A3 Adenosine Receptor Binding: N-(4,6-Diarylpyridin-2-yl)acetamides as Potent and Selective Antagonists

    Journal of Medicinal Chemistry, Vol. 60, Núm. 17, pp. 7502-7511

  2. Enantiospecific Recognition at the A2B Adenosine Receptor by Alkyl 2-Cyanoimino-4-substituted-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylates

    Journal of Medicinal Chemistry, Vol. 60, Núm. 8, pp. 3372-3382

  3. Exploring the influence of the substituent at position 4 in a series of 3,4-dihydropyrimidin-2(1H)-one A2B adenosine receptor antagonists

    Chemistry of Heterocyclic Compounds, Vol. 53, Núm. 3, pp. 316-322

2013

  1. Discovery of 3,4-dihydropyrimidin-2(1 H)-ones as a novel class of potent and selective A2B adenosine receptor antagonists

    ACS Medicinal Chemistry Letters, Vol. 4, Núm. 11, pp. 1031-1036

  2. Selective and potent adenosine A3 receptor antagonists by methoxyaryl substitution on the N-(2,6-diarylpyrimidin-4-yl)acetamide scaffold

    European Journal of Medicinal Chemistry, Vol. 59, pp. 235-242

  3. Synthesis and allosteric modulation of the dopamine receptor by peptide analogs of l-prolyl-l-leucyl-glycinamide (PLG) modified in the l-proline or l-proline and l-leucine scaffolds

    European Journal of Medicinal Chemistry, Vol. 69, pp. 146-158

2011

  1. Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists

    Journal of Medicinal Chemistry, Vol. 54, Núm. 2, pp. 457-471

2009

  1. Synthesis of novel 1-alkyl-8-substituted-3-(3-methoxypropyl) xanthines as putative A2B receptor antagonists

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 9, pp. 3426-3432

2008

  1. 1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 6, pp. 2852-2869

  2. Corrigendum to "1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor" [Bioorg. Med. Chem. 16 (2008) 2852-2869] (DOI:10.1016/j.bmc.2008.01.002)

    Bioorganic and Medicinal Chemistry

  3. Synthesis, adenosine receptor binding and 3D-QSAR of 4-substituted 2-(2′-furyl)-1,2,4-triazolo[1,5-a]quinoxalines

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 4, pp. 2103-2113

2006

  1. Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor

    Journal of Medicinal Chemistry, Vol. 49, Núm. 1, pp. 282-299

2004

  1. 8-Substituted-9-deazaxanthines as adenosine receptor ligands: Design, synthesis and structure-affinity relationships at A 2B

    European Journal of Medicinal Chemistry, Vol. 39, Núm. 10, pp. 879-887

2002

  1. New serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonists: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones

    Journal of Medicinal Chemistry, Vol. 45, Núm. 1, pp. 54-71

2000

  1. Conformationally constrained butyrophenones with affinity for dopamine (D1, D2, D4) and serotonin (5-HT(2A), 5-HT(2B), 5-HT(2C)) receptors: Synthesis of aminomethylbenzo[b]furanones and their evaluation as antipsychotics

    Journal of Medicinal Chemistry, Vol. 43, Núm. 24, pp. 4678-4693

1999

  1. Conformationally constrained butyrophenones with mixed dopaminergic (D2) and serotoninergic (5-HT2(A), 5-HT2(C)) affinities: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and - thienocycloalkanones as putative atypical antipsychotics

    Journal of Medicinal Chemistry, Vol. 42, Núm. 15, pp. 2774-2797

1997

  1. Synthesis, affinity at 5-HT(2A), 5-HT(2B) and 5-HT(2C) serotonin receptors and structure-activity relationships of a series of cyproheptadine analogues

    Chemical and Pharmaceutical Bulletin, Vol. 45, Núm. 5, pp. 842-848

1995

  1. Butyrophenone analogues: Synthesis of 2-methyl-3-ethyl-5-aminoethyl-4,5,6,7-tetrahydroindol-4-ones, and their affinities for d 1 , d 2 and 5-ht 2a receptors

    Bioorganic and Medicinal Chemistry Letters, Vol. 5, Núm. 6, pp. 579-584

1994

  1. Pyridazine derivatives XII. Synthesis and antipsychotic-antidepressant activity of some butyrophenone derivatives of 6-phenylpyridazine

    European Journal of Medicinal Chemistry, Vol. 29, Núm. 11, pp. 831-839

1993

  1. Cyproheptadine analogues: Synthesis, antiserotoninergic activity, and structure‐activity relationships

    Journal of Pharmaceutical Sciences, Vol. 82, Núm. 11, pp. 1090-1093