Departamento de Química Orgánica
Departamento
ANTONIO
MOURIÑO MOSQUERA
Investigador no período 1988-2023
Publicacións nas que colabora con ANTONIO MOURIÑO MOSQUERA (135)
2024
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A vitamin D-based strategy overcomes chemoresistance in prostate cancer
British Journal of Pharmacology, Vol. 181, Núm. 21, pp. 4279-4293
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Pd(0)-Catalyzed-Mediated Synthesis of Vitamin D Compounds
Advanced Synthesis and Catalysis, Vol. 366, Núm. 4, pp. 603-616
2023
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Corrigendum to “Lithocholic acid-based design of noncalcemic vitamin D receptor agonists” [Bioorg. Chem. 111 (2021) 104878] (Bioorganic Chemistry (2021) 111, (S0045206821002558), (10.1016/j.bioorg.2021.104878))
Bioorganic Chemistry
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Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3 (Calcitriol): Refinement of the Side Chain
Journal of Medicinal Chemistry, Vol. 66, Núm. 22, pp. 15326-15339
2022
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Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3
Journal of Medicinal Chemistry, Vol. 65, Núm. 19, pp. 13112-13124
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Efficient Asymmetric Synthesis of an A-Ring Synthon for Pd-Catalyzed Preparation of 1α-Hydroxyvitamin D Metabolites and Analogs
European Journal of Organic Chemistry, Vol. 2022, Núm. 33
2021
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Design, Synthesis, Evaluation and Structure of Allenic 1α,25-Dihydroxyvitamin D3 Analogs with Locked Mobility at C-17
Chemistry - A European Journal, Vol. 27, Núm. 53, pp. 13384-13389
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Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR)
Bioorganic Chemistry, Vol. 115
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Lithocholic acid-based design of noncalcemic vitamin D receptor agonists
Bioorganic Chemistry, Vol. 111
2019
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Synthesis of 28,28,28-trideutero-25-hydroxydihydrotachysterol 2
Journal of Steroid Biochemistry and Molecular Biology, Vol. 185, pp. 248-250
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Remote induction of cellular immune response in mice by anti-meningococcal nanocochleates - nanoproteoliposomes
Science of the Total Environment, Vol. 668, pp. 1055-1063
2018
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Total synthesis of 1α,25-dihydroxyvitamin D
3
analogs modified at the side chain and D-ring
Organic and Biomolecular Chemistry, Vol. 16, Núm. 24, pp. 4563-4569
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Stereoselective synthesis of 25S,26-dihydroxyvitamin D 3
Journal of Steroid Biochemistry and Molecular Biology, Vol. 177, pp. 247-249
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25 S-Adamantyl-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6658-6673
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Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists
Journal of Medicinal Chemistry, Vol. 61, Núm. 11, pp. 4928-4937
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Stereoselective Palladium-Catalyzed Approach to Vitamin D3 Derivatives in Protic Medium
Chemistry - A European Journal, Vol. 24, Núm. 13, pp. 3314-3320
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Studies on the synthesis of vitamin D analogs with aromatic D-ring
Anais da Academia Brasileira de Ciencias, Vol. 90, Núm. 1, pp. 1035-1042
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Synthesis of Side-Chain Locked Analogs of 1α,25-Dihydroxyvitamin D3 Bearing a C17 Methyl Group
Organic Letters, Vol. 20, Núm. 9, pp. 2641-2644
2017
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A new approach to 19-nor-A-ring phosphine oxide for the convergent synthesis of 19-nor-calcitriol
Journal of Steroid Biochemistry and Molecular Biology, Vol. 173, pp. 86-88
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Total synthesis of 1α,25-dihydroxyvitamin D3 (calcitriol) through a Si-assisted allylic substitution
Chemical Communications, Vol. 53, Núm. 58, pp. 8144-8147