Departamento de Química Orgánica
Departamento
FRANCO
FERNANDEZ GONZALEZ
Investigador en el periodo 1976-2018
Publicaciones en las que colabora con FRANCO FERNANDEZ GONZALEZ (128)
2013
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Multicomponent assembly of diverse pyrazin-2(1 H)-one chemotypes
Journal of Organic Chemistry, Vol. 78, Núm. 9, pp. 4402-4409
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Synthesis and allosteric modulation of the dopamine receptor by peptide analogs of l-prolyl-l-leucyl-glycinamide (PLG) modified in the l-proline or l-proline and l-leucine scaffolds
European Journal of Medicinal Chemistry, Vol. 69, pp. 146-158
2012
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A nitro sugar-mediated stereocontrolled synthesis of β2- amino acids: Synthesis of a polyhydroxylated trans-2-aminocyclohexanecarboxylic acid
European Journal of Organic Chemistry, pp. 2969-2979
2011
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Convergent assembly of structurally diverse quinazolines
Organic and Biomolecular Chemistry, Vol. 9, Núm. 2, pp. 351-357
2010
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A 'click chemistry' approach to the straightforward synthesis of new 4-aryl-1,2,3-triazolocarbanucleosides
Arkivoc, Vol. 2010, Núm. 3, pp. 152-168
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Stereocontrolled transformation of nitrohexofuranoses into cyclopentylamines via 2-oxabicyclo[2.2.1]heptanes. Part VI: Synthesis and incorporation of the novel polyhydroxylated 5-aminocyclopent-1-enecarboxylic acids into peptides
Tetrahedron Asymmetry, Vol. 21, Núm. 16, pp. 2021-2026
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Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists
Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 5, pp. 2001-2009
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Synthesis of methyl (±)-3,5-bis(substitutedmethyl)pyrrolidine-2- carboxylates: A convenient approach to proline-mimetics
Tetrahedron, Vol. 66, Núm. 34, pp. 6797-6805
2009
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1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships
Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 10, pp. 3618-3629
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A nitro sugar mediated synthesis of 6-amino-1,5,6-trideoxy-1,5-imino-d-glucitol (6-amino-1,6-dideoxynojirimycin)
Tetrahedron Asymmetry, Vol. 20, Núm. 4, pp. 503-507
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Stereocontrolled transformation of nitrohexofuranoses into cyclopentylamines via 2-oxabicyclo[2.2.1]heptanes. IV: Synthesis of enantiopure methyl (1S,2R,3R,4R,5S)-5-benzyloxycarbonylamino-2,3-isopropylidenedioxy-4-methoxycyclopentanecarboxylate
Tetrahedron Asymmetry, Vol. 20, Núm. 6-8, pp. 892-896
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Synthesis and biological evaluation of 6-substituted purinylcarbanucleosides with a cyclopenta[b]thiophene pseudosugar
Synthesis, pp. 2766-2772
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Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists
Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 18, pp. 6755-6760
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Synthesis of novel 1-alkyl-8-substituted-3-(3-methoxypropyl) xanthines as putative A2B receptor antagonists
Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 9, pp. 3426-3432
2008
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Stereocontrolled transformation of nitrohexofuranoses into cyclopentylamines via 2-oxabicyclo[2.2.1]heptanes. III: synthesis of enantiopure methyl (1S,2S,3R,4S,5R)-2-amino-3,4,5-trihydroxycyclopentanecarboxylate
Tetrahedron Asymmetry, Vol. 19, Núm. 24, pp. 2907-2912
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Synthesis and antiviral activities of novel purinyl- and pyrimidinyl-carbanucleosides derived from indan
Synthesis, pp. 1845-1852
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Synthesis of novel purinyl-1′-homocarbanucleosides based on a cyclopenta[b]pyrazine system
Chemical and Pharmaceutical Bulletin, Vol. 56, Núm. 5, pp. 654-658
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Synthetic applications of polystyrene-supported 1,1,3,3- tetramethylguanidine
Combinatorial Chemistry and High Throughput Screening, Vol. 11, Núm. 10, pp. 843-847
2007
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A novel approach to the synthesis of benzo[b]fluoren-11-ones
Tetrahedron Letters, Vol. 48, Núm. 12, pp. 2147-2149
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Cyclocondensation of (±)-exo,exo-5,6-(isopropylidenedioxy)-3- (pyrrolidino-methylene)bicyclo[2.2.1]heptan-2-one with N-C-N dinucleophiles
Synthesis, pp. 1385-1391