Departamento de Química Orgánica
Departamento
Francisco
Corzana López
Publicacións nas que colabora con Francisco Corzana López (9)
2022
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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry
Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294
2019
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Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
Nature Protocols, Vol. 14, Núm. 1, pp. 86-99
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Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification
ACS Central Science, Vol. 5, Núm. 8, pp. 1417-1424
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Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation
Angewandte Chemie - International Edition, Vol. 58, Núm. 20, pp. 6640-6644
2018
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Chemo- and Regioselective Lysine Modification on Native Proteins
Journal of the American Chemical Society, Vol. 140, Núm. 11, pp. 4004-4017
2017
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Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation
Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18365-18375
2016
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Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
Nature Communications, Vol. 7
2007
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A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition. Dramatic alterations in neomycin-B protonation state upon binding to a 23-mer RNA aptamer
Chemical Communications, Vol. 2, Núm. 2, pp. 174-176
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The Pattern of Distribution of Amino Groups Modulates the Structure and Dynamics of Natural Aminoglycosides: Implications for RNA Recognition
Journal of the American Chemical Society, Vol. 129, Núm. 10, pp. 2849-2865