Departamento de Fisioloxía
Departamento
University of Cambridge
Cambridge, Reino UnidoPublicacións en colaboración con investigadores/as de University of Cambridge (47)
2022
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Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway
International Journal of Molecular Sciences, Vol. 23, Núm. 6
2021
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Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner
Redox Biology, Vol. 41
2020
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Brain-Sparing Sympathofacilitators Mitigate Obesity without Adverse Cardiovascular Effects
Cell Metabolism, Vol. 31, Núm. 6, pp. 1120-1135.e7
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Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis
Molecular Metabolism, Vol. 31, pp. 67-84
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α-Synuclein strains target distinct brain regions and cell types
Nature Neuroscience, Vol. 23, Núm. 1, pp. 21-31
2019
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Hypothalamic dopamine signalling regulates brown fat thermogenesis
Nature Metabolism, Vol. 1, Núm. 8, pp. 811-829
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MCH regulates SIRT1/FoxO1 and reduces POMC neuronal activity to induce hyperphagia, adiposity, and glucose intolerance
Diabetes, Vol. 68, Núm. 12, pp. 2210-2222
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Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption
Cell Reports, Vol. 27, Núm. 11, pp. 3385-3400.e3
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Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development
Blood Advances, Vol. 3, Núm. 16, pp. 2499-2511
2018
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Melanin-Concentrating Hormone acts through hypothalamic kappa opioid system and p70S6K to stimulate acute food intake
Neuropharmacology, Vol. 130, pp. 62-70
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p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1
Nature Communications, Vol. 9, Núm. 1
2017
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A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages
Nature Communications, Vol. 8
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Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
Cell Metabolism, Vol. 26, Núm. 1, pp. 212-229.e12
2015
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Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming
Cell Stem Cell, Vol. 16, Núm. 6, pp. 653-668
2014
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The central nervous system in metabolic syndrome
A Systems Biology Approach to Study Metabolic Syndrome (Springer International Publishing), pp. 137-156
2013
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Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity
Diabetes, Vol. 62, Núm. 11, pp. 3697-3708
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NANOG-dependent function of TET1 and TET2 in establishment of pluripotency
Nature, Vol. 495, Núm. 7441, pp. 370-374
2012
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Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat
Psychopharmacology, Vol. 219, Núm. 3, pp. 783-794
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BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions
Cell, Vol. 149, Núm. 4, pp. 871-885
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Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism
Journal of Pathology, Vol. 227, Núm. 2, pp. 209-222