Publicacións nas que colabora con Manuel José Tena Sempere (96)

2023

  1. Metformin and simvastatin exert additive antitumour effects in glioblastoma via senescence-state: clinical and translational evidence

    eBioMedicine, Vol. 90

2022

  1. Connecting nutritional deprivation and pubertal inhibition via GRK2-mediated repression of kisspeptin actions in GnRH neurons

    Metabolism: Clinical and Experimental, Vol. 129

  2. Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice

    Nature communications, Vol. 13, Núm. 1, pp. 4663

  3. Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway

    International Journal of Molecular Sciences, Vol. 23, Núm. 6

2021

  1. AMP-activated protein kinase (AMPK) signaling in GnRH neurons links energy status and reproduction

    Metabolism: Clinical and Experimental, Vol. 115

  2. Congenital ablation of Tacr2 reveals overlapping and redundant roles of NK2R signaling in the control of reproductive axis

    American Journal of Physiology - Endocrinology and Metabolism, Vol. 320, Núm. 3, pp. E496-E511

  3. Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation

    Nature Metabolism, Vol. 3, Núm. 10, pp. 1415-1431

2020

  1. AMPK-Dependent Mechanisms but Not Hypothalamic Lipid Signaling Mediates GH-Secretory Responses to GHRH and Ghrelin

    Cells, Vol. 9, Núm. 9

  2. Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty

    Cell Metabolism, Vol. 32, Núm. 6, pp. 951-966.e8

2019

  1. Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis

    Metabolism: Clinical and Experimental, Vol. 98, pp. 84-94

  2. Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3

    PLoS Biology, Vol. 17, Núm. 11

2018

  1. Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress

    Cell Reports, Vol. 25, Núm. 2, pp. 413-423.e5

  2. Female puberty overview

    Encyclopedia of Reproduction (Elsevier), pp. 227-237

  3. Intergenerational Influence of paternal obesity on metabolic and reproductive health parameters of the offspring: Male-preferential impact and involvement of kiss1-mediated pathways

    Endocrinology, Vol. 159, Núm. 2, pp. 1005-1018

  4. Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Núm. 45, pp. E10758-E10767

  5. SF1-specific AMPKa1 deletion protects against diet-induced obesity

    Diabetes, Vol. 67, Núm. 11, pp. 2213-2226

  6. SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression

    Nature Communications, Vol. 9, Núm. 1

  7. Sex-Biased Physiological Roles of NPFF1R, the Canonical Receptor of RFRP-3, in Food Intake and Metabolic Homeostasis Revealed by its Congenital Ablation in mice

    Metabolism: Clinical and Experimental, Vol. 87, pp. 87-97

  8. mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol

    Journal of Endocrinology, Vol. 238, Núm. 3, pp. 177-186

2017

  1. Development and validation of a method for precise dating of female puberty in laboratory rodents: The puberty ovarian maturation score (Pub-Score)

    Scientific Reports, Vol. 7