Publicacións en colaboración con investigadores/as de University of Eastern Finland (21)

2024

  1. Discovery and in vitro Evaluation of Novel Serotonin 5-HT2A Receptor Ligands Identified Through Virtual Screening

    ChemMedChem, Vol. 19, Núm. 14

2023

  1. Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia

    Molecules, Vol. 28, Núm. 10

  2. Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents – Design, synthesis, structural studies and pharmacological profiling

    European Journal of Medicinal Chemistry, Vol. 252

  3. Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation

    Journal of enzyme inhibition and medicinal chemistry, Vol. 38, Núm. 1, pp. 2209828

2022

  1. Allosteric modulation of dopamine D2L receptor in complex with Gi1 and Gi2 proteins: the effect of subtle structural and stereochemical ligand modifications

    Pharmacological Reports, Vol. 74, Núm. 2, pp. 406-424

  2. In vitro and in vivo evaluation of antioxidant and neuroprotective properties of antipsychotic D2AAK1

    Neurochemical Research, Vol. 47, Núm. 6, pp. 1778-1789

  3. Multitarget Derivatives of D2AAK1 as Potential Antipsychotics: The Effect of Substitution in the Indole Moiety

    ChemMedChem, Vol. 17, Núm. 15

  4. Understanding dexamethasone kinetics in the rabbit tear fluid: Drug release and clearance from solution, suspension and hydrogel formulations

    European Journal of Pharmaceutics and Biopharmaceutics

2021

  1. Current Situation and Challenges in Vitreous Substitutes

    Macromolecular Bioscience, Vol. 21, Núm. 8

  2. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    Autophagy, Vol. 17, Núm. 1, pp. 1-382

  3. N-(3-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}propyl)-1H-indazole-3-carboxamide (D2AAK3) as a potential antipsychotic: In vitro, in silico and in vivo evaluation of a multi-target ligand

    Neurochemistry International, Vol. 146

2020

  1. N-(2-hydroxyphenyl)-1-[3-(2-oxo-2,3-dihydro-1h-benzimidazol-1-yl)propyl]piperidine-4-carboxamide (d2aak4), a multi-target ligand of aminergic gpcrs, as a potential antipsychotic

    Biomolecules, Vol. 10, Núm. 2

  2. PET study of ocular and blood pharmacokinetics of intravitreal bevacizumab and aflibercept in rats

    European Journal of Pharmaceutics and Biopharmaceutics, Vol. 154, pp. 330-337

2019

  1. Synthesis, pharmacological and structural studies of 5-substituted-3-(1-arylmethyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as multi-target ligands of aminergic GPCRs

    European Journal of Medicinal Chemistry, Vol. 180, pp. 673-689

2018

  1. Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1H-indole (D2AAK1_3) as Dopamine D₂ Receptor Ligand

    Molecules (Basel, Switzerland), Vol. 23, Núm. 9

2016

  1. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Autophagy

  2. Erratum: Corrigendum to “In vitro, molecular modeling and behavioral studies of ‘3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic” (Neurochemistry International (2016) 96 (84–99)(10.1016/j.neuint.2016.03.003)(S0197018616300304))

    Neurochemistry International

  3. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Autophagy, Vol. 12, Núm. 1, pp. 1-222

  4. In vitro, molecular modeling and behavioral studies of 3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic

    Neurochemistry International, Vol. 96, pp. 84-99

  5. Structure-Based Virtual Screening for Dopamine D2 Receptor Ligands as Potential Antipsychotics

    ChemMedChem, Vol. 11, Núm. 7, pp. 718-729