Department of Morphological Science
Department
CARLOS
DIEGUEZ GONZALEZ
University professor
Publications by the researcher in collaboration with CARLOS DIEGUEZ GONZALEZ (54)
2024
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Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance
Molecular Metabolism, Vol. 79
2023
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Small extracellular vesicle targeting of hypothalamic AMPKα1 promotes weight loss in leptin receptor deficient mice
Metabolism: clinical and experimental, Vol. 139, pp. 155350
2022
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Activation of Hypothalamic AMP-Activated Protein Kinase Ameliorates Metabolic Complications of Experimental Arthritis
Arthritis and Rheumatology, Vol. 74, Núm. 2, pp. 212-222
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Olfactomedin 2 deficiency protects against diet-induced obesity
Metabolism: Clinical and Experimental, Vol. 129
2019
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Central nicotine induces browning through hypothalamic κ opioid receptor
Nature Communications, Vol. 10, Núm. 1
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Hypothalamic dopamine signalling regulates brown fat thermogenesis
Nature Metabolism, Vol. 1, Núm. 8, pp. 811-829
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MCH regulates SIRT1/FoxO1 and reduces POMC neuronal activity to induce hyperphagia, adiposity, and glucose intolerance
Diabetes, Vol. 68, Núm. 12, pp. 2210-2222
2018
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Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis
Molecular Metabolism, Vol. 8, pp. 132-143
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p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1
Nature Communications, Vol. 9, Núm. 1
2016
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A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance
Cell Reports, Vol. 16, Núm. 8, pp. 2231-2242
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Hypothalamic kappa opioid receptor mediates both diet-induced and melanin concentrating hormone–induced liver damage through inflammation and endoplasmic reticulum stress
Hepatology, Vol. 64, Núm. 4, pp. 1086-1104
2015
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Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue
Endocrinology, Vol. 156, Núm. 3, pp. 975-986
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Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance
Molecular Metabolism, Vol. 4, Núm. 12, pp. 961-970
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Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-COA and the thermogenic effect of hypothalamic AMPK inhibition in female rats
Endocrinology, Vol. 156, Núm. 3, pp. 947-960
2014
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Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance
Cell Reports, Vol. 9, Núm. 1, pp. 366-377
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Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK
Cell Metabolism, Vol. 20, Núm. 1, pp. 41-53
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GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK
Diabetes, Vol. 63, Núm. 10, pp. 3346-3358
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Hypothalamic KLF4 mediates leptin's effects on food intake via AgRP
Molecular Metabolism, Vol. 3, Núm. 4, pp. 441-451
2013
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Central melanin-concentrating hormone influences liver and adipose metabolism via specific hypothalamic nuclei and efferent autonomic/JNK1 pathways
Gastroenterology, Vol. 144, Núm. 3
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Nesfatin-1 in human and murine cardiomyocytes: Synthesis, secretion, and mobilization of GLUT-4
Endocrinology, Vol. 154, Núm. 12, pp. 4757-4767