MARIA DOLORES
VIÑA CASTELAO
Profesora titular de universidade
MARIA LOURDES
SANTANA PENIN
Profesora emérita de universidade
Publicacións nas que colabora con MARIA LOURDES SANTANA PENIN (31)
2015
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3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases
ChemMedChem, Vol. 10, Núm. 12, pp. 2071-2079
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Potent and selective MAO-B inhibitory activity: Amino- versus nitro-3-arylcoumarin derivatives
Bioorganic and Medicinal Chemistry Letters, Vol. 25, Núm. 3, pp. 642-648
2014
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Insight into the functional and structural properties of 3-arylcoumarin as an interesting scaffold in monoamine oxidase B inhibition
ChemMedChem, Vol. 9, Núm. 7, pp. 1488-1500
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Synthesis, biological evaluation and structure-activity relationships of new phthalazinedione derivatives with vasorelaxant activity
European Journal of Medicinal Chemistry, Vol. 82, pp. 407-417
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Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases
Future Medicinal Chemistry, Vol. 6, Núm. 4, pp. 371-383
2013
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MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, invitro Study, and Docking Calculations
ChemMedChem, Vol. 8, Núm. 6, pp. 956-966
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Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: Synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study
European Journal of Medicinal Chemistry, Vol. 63, pp. 151-161
2012
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3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease
MedChemComm, Vol. 3, Núm. 2, pp. 213-218
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8-Substituted 3-Arylcoumarins as Potent and Selective MAO-B Inhibitors: Synthesis, Pharmacological Evaluation, and Docking Studies
ChemMedChem, Vol. 7, Núm. 3, pp. 464-470
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Focusing on new monoamine oxidase inhibitors: Differently substituted coumarins as an interesting scaffold
Current Topics in Medicinal Chemistry, Vol. 12, Núm. 20, pp. 2210-2239
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Hydroxycoumarins as selective MAO-B inhibitors
Bioorganic and Medicinal Chemistry Letters, Vol. 22, Núm. 1, pp. 258-261
2011
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MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins
Bioorganic and Medicinal Chemistry Letters, Vol. 21, Núm. 14, pp. 4224-4227
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Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors
Journal of Medicinal Chemistry, Vol. 54, Núm. 20, pp. 7127-7137
2010
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New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors
Bioorganic and Medicinal Chemistry Letters, Vol. 20, Núm. 17, pp. 5157-5160
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Synthesis and vasorelaxant and platelet antiaggregatory activities of a new series of 6-Halo-3-phenylcoumarins
Molecules, Vol. 15, Núm. 1, pp. 270-279
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Synthesis of carbocyclic pyrimidine nucleosides using the Mitsunobu reaction: O2- vs. N1-alkylation
Helvetica Chimica Acta, Vol. 93, Núm. 2, pp. 309-313
2009
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A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors
Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 12, pp. 3268-3270
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Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors
Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 17, pp. 5053-5055
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Synthesis of regioisomeric functionalized benzodifurans and angelicins
Helvetica Chimica Acta, Vol. 92, Núm. 7, pp. 1309-1314
2008
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Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors
Journal of Medicinal Chemistry, Vol. 51, Núm. 21, pp. 6740-6751