Publikationen (54) Publikationen von EMILIO JOSE LENCE QUINTANA

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2026

  1. Antibacterial activity of enmetazobactam against Acinetobacter spp.: a molecular dissection of mechanism of action and resistance determinants

    Antimicrobial agents and chemotherapy, Vol. 70, Núm. 2, pp. e0120625

  2. Disarming carbapenemase-producing Acinetobacter baumannii: high potency of the novel therapeutic combination of meropenem and the innovative diazabicyclooctane β-lactamase inhibitor pilabactam (formerly ANT3310)

    Antimicrobial Agents and Chemotherapy, Vol. 70, Núm. 4

  3. Zwitterionic Penicillin-Derived Sulfone Inhibitor for Combating β-Lactamase-Mediated Antibiotic Resistance

    ChemMedChem, Vol. 21, Núm. 9

2025

  1. Advancements in the fight against globally distributed OXA-48 carbapenemase: evaluating the new generation of carbapenemase inhibitors

    Antimicrobial Agents and Chemotherapy, Vol. 69, Núm. 2

  2. Functional and structural analyses of amino acid sequence variation in PDC β-lactamase reveal different mechanistic pathways toward cefiderocol resistance in Pseudomonas aeruginosa

    Antimicrobial agents and chemotherapy, Vol. 69, Núm. 7, pp. e0029225

  3. Methylglyoxal Alone or Combined with Light-Emitting Diodes/Complex Electromagnetic Fields Represent an Effective Response to Microbial Chronic Wound Infections

    Antibiotics, Vol. 14, Núm. 4, pp. 396

2024

  1. High-affinity A/T-rich DNA binding with a dimeric bisbenzamidine

    NAR Molecular Medicine, Vol. 1, Núm. 4

  2. In vivo emergence of resistance to ceftazidime/avibactam through modification of chromosomal AmpC β-lactamase in Klebsiella aerogenes

    Antimicrobial Agents and Chemotherapy, Vol. 68, Núm. 12

  3. Modulation of the photobehavior of gefitinib and its phenolic metabolites by human transport proteins

    Frontiers in Pharmacology, Vol. 15

  4. Novel Penicillin-Based Sulfone-Siderophore Conjugates for Restoring β-Lactam Antibiotic Efficacy

    ACS Omega, Vol. 9, Núm. 24, pp. 26484-26494

2023

  1. Antimicrobial Activity of Cefiderocol against the Carbapenemase-Producing Enterobacter cloacae Complex and Characterization of Reduced Susceptibility Associated with Metallo-β-Lactamase VIM-1

    Antimicrobial agents and chemotherapy, Vol. 67, Núm. 5, pp. e0150522

  2. In Silico Simulations and Functional Cell Studies Evidence Similar Potency and Distinct Binding of Pacific and Caribbean Ciguatoxins

    Exposure and Health, Vol. 15, Núm. 3, pp. 641-660

  3. In vitro development of imipenem/relebactam resistance in KPC-producing Klebsiella pneumoniae involves multiple mutations including OmpK36 disruption and KPC modification

    International Journal of Antimicrobial Agents, Vol. 62, Núm. 4

  4. Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme—A molecular insight †

    Frontiers in Molecular Biosciences, Vol. 10

  5. Singlet oxygen and radical-mediated mechanisms in the oxidative cellular damage photosensitized by the protease inhibitor simeprevir

    Free Radical Biology and Medicine, Vol. 194, pp. 42-51

2022

  1. Discovery of 3H-pyrrolo[2,3-c]quinolines with activity against Mycobacterium tuberculosis by allosteric inhibition of the glutamate-5-kinase enzyme

    European Journal of Medicinal Chemistry, Vol. 232

  2. Regioselective Synthesis of 2-Aryl-5-cyano-1-(2-hydroxyaryl)-1 H-imidazole-4-carboxamides Self-Assisted by a 2-Hydroxyaryl Group

    ACS Omega, Vol. 7, Núm. 27, pp. 23289-23301

  3. Switching from ultrafast electron transfer to proton transfer in excited drug-protein complexes upon biotransformation

    Chemical Science, Vol. 13, Núm. 33, pp. 9644-9654

2021

  1. 6-Halopyridylmethylidene Penicillin-Based Sulfones Efficiently Inactivate the Natural Resistance of Pseudomonas aeruginosa to β-Lactam Antibiotics

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 6310-6328

  2. Bicyclic Boronate β-Lactamase Inhibitors: The Present Hope against Deadly Bacterial Pathogens

    Advanced Therapeutics, Vol. 4, Núm. 5