EMILIO JOSE
LENCE QUINTANA
Investigador no período 2013-2018
José Manuel
Otero Casas
Publicacións nas que colabora con José Manuel Otero Casas (7)
2023
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Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme—A molecular insight †
Frontiers in Molecular Biosciences, Vol. 10
2019
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Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme
Organic Chemistry Frontiers, Vol. 6, Núm. 17, pp. 3127-3135
2015
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Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct
Journal of the American Chemical Society, Vol. 137, Núm. 29, pp. 9333-9343
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Irreversible covalent modification of type i dehydroquinase with a stable Schiff base
Organic and Biomolecular Chemistry, Vol. 13, Núm. 3, pp. 706-716
2014
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Insights into substrate binding and catalysis in bacterial type i dehydroquinase
Biochemical Journal, Vol. 462, Núm. 3, pp. 415-424
2013
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Mechanistic basis of the inhibition of type II dehydroquinase by (2 S)- and (2 R)-2-benzyl-3-dehydroquinic acids
ACS Chemical Biology, Vol. 8, Núm. 3, pp. 568-577
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Mycobacterium tuberculosis shikimate kinase inhibitors: Design and simulation studies of the catalytic turnover
Journal of the American Chemical Society, Vol. 135, Núm. 33, pp. 12366-12376