Publicacións (123) Publicacións de CONCEPCION GONZALEZ BELLO

2023

  1. Antimicrobial Activity of Cefiderocol against the Carbapenemase-Producing Enterobacter cloacae Complex and Characterization of Reduced Susceptibility Associated with Metallo-β-Lactamase VIM-1

    Antimicrobial agents and chemotherapy, Vol. 67, Núm. 5, pp. e0150522

  2. In Silico Simulations and Functional Cell Studies Evidence Similar Potency and Distinct Binding of Pacific and Caribbean Ciguatoxins

    Exposure and Health, Vol. 15, Núm. 3, pp. 641-660

  3. In vitro development of imipenem/relebactam resistance in KPC-producing Klebsiella pneumoniae involves multiple mutations including OmpK36 disruption and KPC modification

    International Journal of Antimicrobial Agents, Vol. 62, Núm. 4

  4. Interplay between OXA-10 β-Lactamase Production and Low Outer-Membrane Permeability in Carbapenem Resistance in Enterobacterales

    Antibiotics, Vol. 12, Núm. 6

  5. Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme—A molecular insight †

    Frontiers in Molecular Biosciences, Vol. 10

  6. Siderophores: Chemical tools for precise antibiotic delivery

    Bioorganic and Medicinal Chemistry Letters, Vol. 87

  7. Singlet oxygen and radical-mediated mechanisms in the oxidative cellular damage photosensitized by the protease inhibitor simeprevir

    Free Radical Biology and Medicine, Vol. 194, pp. 42-51

2022

  1. Discovery of 3H-pyrrolo[2,3-c]quinolines with activity against Mycobacterium tuberculosis by allosteric inhibition of the glutamate-5-kinase enzyme

    European Journal of Medicinal Chemistry, Vol. 232

  2. Regioselective Synthesis of 2-Aryl-5-cyano-1-(2-hydroxyaryl)-1 H-imidazole-4-carboxamides Self-Assisted by a 2-Hydroxyaryl Group

    ACS Omega, Vol. 7, Núm. 27, pp. 23289-23301

  3. Selection of AmpC β-Lactamase Variants and Metalloβ- Lactamases Leading to Ceftolozane/Tazobactam and Ceftazidime/Avibactam Resistance during Treatment of MDR/ XDR Pseudomonas aeruginosa Infections

    Antimicrobial Agents and Chemotherapy, Vol. 66, Núm. 2

  4. Switching from ultrafast electron transfer to proton transfer in excited drug-protein complexes upon biotransformation

    Chemical Science, Vol. 13, Núm. 33, pp. 9644-9654

2021

  1. 6-Halopyridylmethylidene Penicillin-Based Sulfones Efficiently Inactivate the Natural Resistance of Pseudomonas aeruginosa to β-Lactam Antibiotics

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 6310-6328

  2. Activity of imipenem, meropenem, cefepime, and sulbactam in combination with the β-lactamase inhibitor ln-1-255 against acinetobacter spp.

    Antibiotics, Vol. 10, Núm. 2, pp. 1-15

  3. Bicyclic Boronate β-Lactamase Inhibitors: The Present Hope against Deadly Bacterial Pathogens

    Advanced Therapeutics, Vol. 4, Núm. 5

  4. Crambescin C1 Acts as A Possible Substrate of iNOS and eNOS Increasing Nitric Oxide Production and Inducing In Vivo Hypotensive Effect

    Frontiers in Pharmacology, Vol. 12

  5. Molecular Basis of Bicyclic Boronate β-Lactamase Inhibitors of Ultrabroad Efficacy – Insights From Molecular Dynamics Simulation Studies

    Frontiers in Microbiology, Vol. 12

  6. Molecular mechanisms driving the in vivo development of OXA-10-mediated resistance to ceftolozane/tazobactam and ceftazidime/avibactam during treatment of XDR Pseudomonas aeruginosa infections

    The Journal of antimicrobial chemotherapy, Vol. 76, Núm. 1, pp. 91-100

2020

  1. 6-Arylmethylidene Penicillin-Based Sulfone Inhibitors for Repurposing Antibiotic Efficiency in Priority Pathogens

    Journal of Medicinal Chemistry, Vol. 63, Núm. 7, pp. 3737-3755

  2. Characterization of Locally Excited and Charge-Transfer States of the Anticancer Drug Lapatinib by Ultrafast Spectroscopy and Computational Studies

    Chemistry - A European Journal, Vol. 26, Núm. 68, pp. 15922-15930

  3. Investigation of metabolite-protein interactions by transient absorption spectroscopy and in silico methods

    Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, Vol. 226