Publicacións (42) Publicacións de JOSE ANGEL FONTENLA GIL

2023

  1. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    European Journal of Medicinal Chemistry, Vol. 248

2021

  1. Gamma-decanolactone: Preliminary evaluation as potential antiparkinsonian drug

    European Journal of Pharmacology, Vol. 906

2020

  1. Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies

    Bioorganic Chemistry, Vol. 101

  2. Gamma-decanolactone attenuates acute and chronic seizures in mice: a possible role of adenosine A1 receptors

    Behavioural pharmacology, Vol. 31, Núm. 6, pp. 544-552

  3. Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson's disease therapy

    Bioorganic Chemistry, Vol. 104

2018

  1. Alkaloids as MAO-A inhibitors: Towards the final solution for depression and anxiety

    Psychiatric and Mood Diseases and the Natural Compounds: An Approach to the Future Medical Tool (Nova Science Publishers, Inc.), pp. 169-192

2017

  1. Aporphine alkaloids and their antioxidant medical application: From antineoplastic agents to motor dysfunction diseases

    Current Organic Chemistry, Vol. 21, Núm. 4, pp. 342-347

  2. MAO inhibitory activity of bromo-2-phenylbenzofurans: Synthesis,: in vitro study, and docking calculations

    MedChemComm, Vol. 8, Núm. 9, pp. 1788-1796

2016

  1. Neuropharmacological effects of the ethanolic extract of Sida acuta

    Brazilian Journal of Pharmacognosy, Vol. 26, Núm. 2, pp. 209-215

2015

  1. Anxiolytic-like effects of 7H-benzo[e]perimidin-7-one derivatives through elevated plus-maze test in mice

    Current Topics in Medicinal Chemistry, Vol. 15, Núm. 17, pp. 1750-1754

2014

  1. Comparison of the antidepressive effects of trans-resveratrol and 5-methoxy-7H-dibenzo[de,h]quinolin-7-one.

    Current topics in medicinal chemistry, Vol. 14, Núm. 2, pp. 234-238

  2. Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

    Future Medicinal Chemistry, Vol. 6, Núm. 4, pp. 371-383

2013

  1. Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: Synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

    European Journal of Medicinal Chemistry, Vol. 63, pp. 151-161

2008

  1. ANXIOLYTIC/HYPNOTIC AND MIORRELAXANT ACTIVITIES OF AZEPINE DERIVATIVES

    METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY

  2. HOMOCYSTINE-INDUCED DAMAGE IN DOPAMINERGIC NIGROSTRIATAL PATHWAYS

    METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY

2003

  1. New arylpiperazine derivatives with high affinity for α1A, D2 and 5-HT2A receptors

    Bioorganic and Medicinal Chemistry Letters, Vol. 13, Núm. 2, pp. 175-178

  2. Synthesis of glycosyl derivatives as dopamine prodrugs: Interaction with glucose carrier GLUT-1

    Organic and Biomolecular Chemistry, Vol. 1, Núm. 5, pp. 767-771

2000

  1. Binding and preliminary evaluation of 5-hydroxy- and 10-hydroxy- 2,3,12,12a-tetrahydro-1H-[1]benzoxepino[2,3,4-ij]isoquinolines as dopamine receptor ligands

    Journal of Medicinal Chemistry, Vol. 43, Núm. 4, pp. 599-608

  2. Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: Synthesis and determination of affinities at D2, 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors

    European Journal of Medicinal Chemistry, Vol. 35, Núm. 1, pp. 83-95

  3. Conformationally constrained butyrophenones with affinity for dopamine (D1, D2, D4) and serotonin (5-HT(2A), 5-HT(2B), 5-HT(2C)) receptors: Synthesis of aminomethylbenzo[b]furanones and their evaluation as antipsychotics

    Journal of Medicinal Chemistry, Vol. 43, Núm. 24, pp. 4678-4693