MARIA JOAO
CORREIA PINTO CARVALHO DE MATOS
Profesora titular de universidade
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University of Cambridge
Cambridge, Reino UnidoPublicacións en colaboración con investigadores/as de University of Cambridge (15)
2022
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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry
Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294
2020
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Sequential dual site-selective protein labelling enabled by lysine modification
Bioorganic and Medicinal Chemistry, Vol. 28, Núm. 22
2019
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Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
Nature Protocols, Vol. 14, Núm. 1, pp. 86-99
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Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification
ACS Central Science, Vol. 5, Núm. 8, pp. 1417-1424
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Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent
Methods in Molecular Biology (Humana Press Inc.), pp. 25-37
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Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation
Angewandte Chemie - International Edition, Vol. 58, Núm. 20, pp. 6640-6644
2018
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A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis
Peptide Science, Vol. 110, Núm. 3
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A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging
Chemical Science, Vol. 9, Núm. 17, pp. 4185-4189
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Chemo- and Regioselective Lysine Modification on Native Proteins
Journal of the American Chemical Society, Vol. 140, Núm. 11, pp. 4004-4017
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Learning from nature: The role of albumin in drug delivery
Future Medicinal Chemistry
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Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates
Chemistry - A European Journal, Vol. 24, Núm. 47, pp. 12250-12253
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Trends in patented chromones for skin diseases
Pharmaceutical patent analyst, Vol. 7, Núm. 3, pp. 107-109
2017
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Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation
Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18365-18375
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Trends in therapeutic drug conjugates for bacterial diseases: a patent review
Expert Opinion on Therapeutic Patents, Vol. 27, Núm. 2, pp. 179-189
2016
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Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
Nature Communications, Vol. 7