José Manuel
Brea Floriani
Profesor titular de universidade
University of Bologna
Bolonia, ItaliaPublikationen in Zusammenarbeit mit Forschern von University of Bologna (4)
2024
2022
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Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease
Journal of Medicinal Chemistry, Vol. 65, Núm. 6, pp. 4909-4925
2021
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From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
European Journal of Medicinal Chemistry, Vol. 225
2020
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Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6
Journal of Medicinal Chemistry, Vol. 63, Núm. 17, pp. 9360-9390