José Manuel
Brea Floriani
Senior university lecturer
Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas
Madrid, EspañaPublications in collaboration with researchers from Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (6)
2024
2020
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Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6
Journal of Medicinal Chemistry, Vol. 63, Núm. 17, pp. 9360-9390
2018
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Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin
Scientific Reports, Vol. 8, Núm. 1
2017
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Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson's disease
Future Medicinal Chemistry, Vol. 9, Núm. 8, pp. 731-748
2014
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Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitors
Journal of Medicinal Chemistry, Vol. 57, Núm. 20, pp. 8590-8607
2012
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Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds
Journal of Medicinal Chemistry, Vol. 55, Núm. 7, pp. 3274-3284