José Manuel
Brea Floriani
Profesor titular de universidade
Institut d'Investigacions Biomèdiques August Pi i Sunyer
Barcelona, EspañaPublicacións en colaboración con investigadores/as de Institut d'Investigacions Biomèdiques August Pi i Sunyer (5)
2022
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Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 236
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Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease
Journal of Medicinal Chemistry, Vol. 65, Núm. 6, pp. 4909-4925
2021
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From the Design to the in Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 5429-5446
2012
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Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds
Journal of Medicinal Chemistry, Vol. 55, Núm. 7, pp. 3274-3284
2002
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New serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonists: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones
Journal of Medicinal Chemistry, Vol. 45, Núm. 1, pp. 54-71