José Manuel
Brea Floriani
Profesor titular de universidade
Ana
Martínez
Publicacións nas que colabora con Ana Martínez (7)
2017
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Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson's disease
Future Medicinal Chemistry, Vol. 9, Núm. 8, pp. 731-748
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Targeting PDE10A GAF domain with small molecules: A way for allosteric modulation with anti-inflammatory effects
Molecules, Vol. 22, Núm. 9
2014
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Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitors
Journal of Medicinal Chemistry, Vol. 57, Núm. 20, pp. 8590-8607
2013
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Unraveling phosphodiesterase surfaces. Identification of phosphodiesterase 7 allosteric modulation cavities
European Journal of Medicinal Chemistry, Vol. 70, pp. 781-788
2012
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Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds
Journal of Medicinal Chemistry, Vol. 55, Núm. 7, pp. 3274-3284
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Identification in Silico and experimental validation of novel phosphodiesterase 7 inhibitors with efficacy in experimental autoimmune encephalomyelitis mice
ACS Chemical Neuroscience, Vol. 3, Núm. 10, pp. 793-803
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Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model
European Journal of Medicinal Chemistry, Vol. 47, Núm. 1, pp. 175-185