MARTA MARIA
VARELA REY
Investigadora distinguida
Centro de Investigación Cooperativa en Biotecnología
Zamudio, EspañaPublikationen in Zusammenarbeit mit Forschern von Centro de Investigación Cooperativa en Biotecnología (31)
2024
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p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
Cell Reports Medicine, Vol. 5, Núm. 2
2023
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Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, Vol. 77, Núm. 5, pp. 1654-1669
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Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Cell Metabolism, Vol. 35, Núm. 8, pp. 1373-1389.e8
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Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function
Molecular Metabolism, Vol. 75
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The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent
Hepatology (Baltimore, Md.), Vol. 78, Núm. 3, pp. 878-895
2022
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HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models
Advanced Drug Delivery Reviews, Vol. 181
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Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
Journal of Hepatology, Vol. 76, Núm. 1, pp. 11-24
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Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis
Journal of Hepatology, Vol. 77, Núm. 1, pp. 15-28
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Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals
Hepatology, Vol. 75, Núm. 3, pp. 550-566
2021
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Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury
JHEP Reports, Vol. 3, Núm. 3
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E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment
Cancer Research, Vol. 81, Núm. 11, pp. 2874-2887
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Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH
Journal of Hepatology, Vol. 75, Núm. 1, pp. 34-45
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O-GlcNAcylated p53 in the liver modulates hepatic glucose production
Nature Communications, Vol. 12, Núm. 1
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The L-α-Lysophosphatidylinositol/G Protein–Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis
Hepatology, Vol. 73, Núm. 2, pp. 606-624
2020
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HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis
The Journal of clinical investigation, Vol. 130, Núm. 7, pp. 3848-3864
2019
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SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer
EBioMedicine, Vol. 40, pp. 406-421
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Ubiquitin-Like Post-Translational Modifications (Ubl-PTMs): Small Peptides with Huge Impact in Liver Fibrosis
Cells, Vol. 8, Núm. 12
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miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease
Molecular Metabolism, Vol. 29, pp. 40-54
2018
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MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis
Cell Death and Disease, Vol. 9, Núm. 10
2017
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A morphological method for ammonia detection in liver
PLoS ONE, Vol. 12, Núm. 3