ERNESTO
CANO RUBIO
Forscher in der Zeit 1989-2018
MARIA REYES
LAGUNA FRANCIA
Catedrática de universidade
Publikationen, an denen er mitarbeitet MARIA REYES LAGUNA FRANCIA (12)
2017
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3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation
ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933
2008
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2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: Design, synthesis, and SAR studies
Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 2, pp. 793-797
2007
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Design, synthesis, and structure-activity relationships of a novel series of 5-alkylidenepyridazin-3(2H)-ones with a non-cAMP-based antiplatelet activity
Journal of Medicinal Chemistry, Vol. 50, Núm. 26, pp. 6476-6484
2006
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Pyridazines part 41: Synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl) pyridazin-3(2H)-ones
Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 4, pp. 1080-1083
2004
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Pyridazines. Part 36: Synthesis and antiplatelet activity of 5-substituted-6-phenyl-3(2H)-pyridazinones
Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 2, pp. 321-324
2002
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Pyridazines. Part 28: 5-Alkylidene-6-phenyl-3(2H)-pyridazinones, a new family of platelet aggregation inhibitors
Bioorganic and Medicinal Chemistry Letters, Vol. 12, Núm. 12, pp. 1575-1577
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Pyridazines. Part 31: Synthesis and antiplatelet activity of 4,5-disubstituted-6-phenyl-3(2H)-pyridazinones
Chemical and Pharmaceutical Bulletin, Vol. 50, Núm. 12, pp. 1574-1577
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Pyridazines. Part XXIX: Synthesis and platelet aggregation inhibition activity of 5-substituted-6-phenyl-3(2H)-pyridazinones. Novel aspects of their biological actions
Bioorganic and Medicinal Chemistry, Vol. 10, Núm. 9, pp. 2873-2882
1999
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AM1 theoretical study, synthesis and biological evaluation of some benzofuran analogues of anti-inflammatory arylalkanoic acids
European Journal of Pharmaceutical Sciences, Vol. 7, Núm. 2, pp. 161-166
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Pyridazines XVIII. 6-Aryl-3(2H)-pyridazinones inhibit calcium influx in stimulated platelets
Biological and Pharmaceutical Bulletin, Vol. 22, Núm. 12, pp. 1376-1379
1997
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Pyridazines. XIII. Synthesis of 6-aryl-5-oxygenated substituted-3(2H)- pyridazinones and evaluation as platelet aggregation inhibitors
Chemical and Pharmaceutical Bulletin, Vol. 45, Núm. 7, pp. 1151-1155
1994
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Synthesis and evaluation of some 4,5-disubstituted 6-phenyl-3(2H)-pyridazinones as hypotensive agents
European Journal of Medicinal Chemistry